Advanced Healthcare Materials, EarlyView.A paracrine factor local gradient (PFLG)‐generating system enables microvessel penetration across 3D hepatocyte tissues. The resulting vascularized constructs recapitulate hepatic sinusoidal hepatocyte—endothelial contact architecture and enhance hepatic functions in vitro.
Yen‐Hsiang Huang +2 more
wiley +1 more source
Endoscopic lateral transorbital approach for resection of a recurrent trigeminal schwannoma: Two-dimensional operative video. [PDF]
Surg Neurol IntGómez-Amador JL +8 more
europepmc +1 more source
Dynamic Modulation of the Microenvironment Promotes Functional Maturation of Engineered Tissues
Advanced Healthcare Materials, EarlyView.Engineered tissues lack the dynamic microenvironment of native tissues. A biocompatible, diffusible small molecule to dynamically modulate tissue microenvironments during maturation is used. Timing‐dependent modulation yields distinct outcomes, producing thicker, more native‐like blood vessels, stronger and more mature cardiac tissues, and optimized ...
Eric Silberman +7 more
wiley +1 more source
Requirements and Use Cases for eHealth Solutions in Flexible Assertive Community Treatment Teams: Design Science Study. [PDF]
JMIR Form ResBønes E, Granja C, Solvoll T.
europepmc +1 more source
Video Description Schemes in Broadcasting
, 2006 The large amount of information in audiovisual archives makes it quite difficult to efficiently locate a resource for re-use or re-purposing. In response to the needs of industries and users to solve this problem, different organisations have recently initiated active work in the definition of interoperable frameworks and representation for metadata ...
openaire +1 more source
Advanced Healthcare Materials, EarlyView.ABSTRACT The ascent of novel alternative methods in drug development spotlights the dual needs for improved biological fidelity to in vivo, along with reproducibility, especially in regulatory applications. The need for pre‐clinical models of patient‐derived endometriosis lesions motivates the development of a vascularizable, completely synthetic ...
Lauren Pruett +7 more
wiley +1 more source
Surgical video - technical nuances of performing a selective thoracic fusion for a Lenke 1B adolescent scoliotic curve. [PDF]
Surg Neurol IntFaraj D, Fowler HF, Galgano M.
europepmc +1 more source
Copper–Collagen Interactions Regulate the Mechanical and Invasive Properties of Tumor Spheroids
Advanced Healthcare Materials, EarlyView.Ionic copper is investigated as a modulator of tumor spheroid growth and invasiveness in a 3D microfluidic glioblastoma model. Copper exposure alters metabolic activity, cytoskeletal organization, protrusion dynamics, and EMT‐related phenotypes in a dose‐ and timing‐dependent manner, revealing how copper bioavailability shapes tumor aggressiveness ...
Paula Guerrero‐López +5 more
wiley +1 more source
Simultaneous endoscopic endonasal treatment of a GH-secreting PitNET and paraclinoid aneurysm in a hybrid operating room - 2D operative video. [PDF]
Surg Neurol IntGómez-Amador JL +8 more
europepmc +1 more source
Bioengineered 3D hPSC‐Cholangiocyte Ducts With Physiological Signals for Biliary Disease Modeling
Advanced Healthcare Materials, EarlyView.Tian and colleagues generated a bioengineered bile duct from human pluripotent stem cell (hPSC)‐derived intrahepatic cholangiocytes within a high‐throughput, 384‐well platform to systematically examine the influence of biliary physiological signals including fluid flow, stromal cells and bile acids, and models intrahepatic biliary disease progression ...
Britney Tian +10 more
wiley +1 more source