Urban gardens foster year-round activity of bumble bee queens. [PDF]
Finn SR, Erickson E, Crone EE.
europepmc +1 more source
Deep Learning Prediction of O‐Glycopeptide Tandem Mass Spectra Enhances O‐Glycoproteomics
DeepGPO integrates Transformer and graph neural networks with tailored training strategies, including data augmentation, loss re‐weighting, and pre‐training, to achieve high‐quality O‐glycopeptide MS/MS spectra prediction. The predicted MS/MS spectra are used to localize O‐glycosylation sites from HCD MS/MS data, enhancing O‐glycoproteomics analysis ...
Yu Zong, Yuxin Wang, Liang Qiao
wiley +1 more source
Diagnosis of prolonged grief disorder among older adults: mapping physicians' knowledge and practice, and evaluating the effectiveness of a brief targeted training program. [PDF]
Manevich A, Shefet D, Orion Y, Elior N.
europepmc +1 more source
Vascular Aβ40 corrupts GRP78 phase behavior in brain endothelial cells, sustaining IRE1α–TRAF2–JNK signaling and driving apoptosis, tight junction loss, and blood–brain barrier failure in cerebral amyloid angiopathy. Pharmacological IRE1α inhibition restores vascular integrity, reduces leakage, and improves functional outcomes, revealing a targetable ...
Honglin Zheng +19 more
wiley +1 more source
Challenges and Opportunities for Theory-Grounded Data Visualization in Extended Reality. [PDF]
Bueckle A +9 more
europepmc +1 more source
A Monolithic Janus Hydrogel Pressure Sensor for Wearable Motion and Physiological Monitoring
This work reports a monolithic Janus hydrogel pressure sensor featuring integrated conductive PEDOT and insulating PEGDA layers. The fabricated device achieves a rapid response time, a wide operating range, and good cyclic durability. The sensor demonstrates robust performance in tracking dynamic human joint motions, offering a scalable strategy for ...
Syed Atif Ali +7 more
wiley +1 more source
Exploring global variations in the quality of patient information videos for keratoplasty. [PDF]
Stanley DL +3 more
europepmc +1 more source
Drop‐location sensitivity remains a key barrier to practical droplet‐based electricity generators (DEGs). Here, a polydimethylsiloxane slippery covalently attached liquid (PDMS‐SCAL)‐coated interface promotes droplet sliding instead of splitting or bouncing, allowing stable electricity generation from randomly falling raindrops. The resulting PDMS‐SCAL‐
Jung Bin Yang +6 more
wiley +1 more source
'We gout your back': a qualitative study to co-design educational gout resources with Pacific people in Aotearoa New Zealand. [PDF]
Tu'akoi S +8 more
europepmc +1 more source
A Novel Pak1 Activator Ameliorates ER Stress for HFpEF Therapy
Chronic metabolic stress is a major contributor to HFpEF progression. Under prolonged metabolic stress, Pak1 activity becomes impaired, contributing to disrupted ER proteostasis, cardiomyocyte apoptosis, fibrosis, and diastolic dysfunction. Mechanistically, Pak1 overexpression activates the ERK1/2–MNK1–eIF4E signaling axis, promotes translational ...
Honglin Xu +17 more
wiley +1 more source

