A thermo‐responsive poly(2‐oxazoline)‐based injectable formulation is developed to modulate intraocular pressure (IOP) in both normal and hypotonic eyes. By adjusting the PEG content, the aggregation behavior is finely tuned, enabling IOP elevation without long‐term deposition.
Yuji Tanaka +2 more
wiley +1 more source
Video-Based Skill Assessment for Postoperative T-Tube Nursing is Associated with Improved Clinical Outcomes and Patient Satisfaction: A Single-Center Retrospective Comparative Study. [PDF]
Zhang B, Li Y, Zhao H.
europepmc +1 more source
A paracrine factor local gradient (PFLG)‐generating system enables microvessel penetration across 3D hepatocyte tissues. The resulting vascularized constructs recapitulate hepatic sinusoidal hepatocyte—endothelial contact architecture and enhance hepatic functions in vitro.
Yen‐Hsiang Huang +2 more
wiley +1 more source
The quality and reliability of YouTube video resources concerning patient education for Parkinson's disease: An electronic media-based study. [PDF]
Liu X, Wang S, Gan L, Wang Y, Jiang L.
europepmc +1 more source
Dynamic Modulation of the Microenvironment Promotes Functional Maturation of Engineered Tissues
Engineered tissues lack the dynamic microenvironment of native tissues. A biocompatible, diffusible small molecule to dynamically modulate tissue microenvironments during maturation is used. Timing‐dependent modulation yields distinct outcomes, producing thicker, more native‐like blood vessels, stronger and more mature cardiac tissues, and optimized ...
Eric Silberman +7 more
wiley +1 more source
ABSTRACT The ascent of novel alternative methods in drug development spotlights the dual needs for improved biological fidelity to in vivo, along with reproducibility, especially in regulatory applications. The need for pre‐clinical models of patient‐derived endometriosis lesions motivates the development of a vascularizable, completely synthetic ...
Lauren Pruett +7 more
wiley +1 more source
Copper–Collagen Interactions Regulate the Mechanical and Invasive Properties of Tumor Spheroids
Ionic copper is investigated as a modulator of tumor spheroid growth and invasiveness in a 3D microfluidic glioblastoma model. Copper exposure alters metabolic activity, cytoskeletal organization, protrusion dynamics, and EMT‐related phenotypes in a dose‐ and timing‐dependent manner, revealing how copper bioavailability shapes tumor aggressiveness ...
Paula Guerrero‐López +5 more
wiley +1 more source
Assessment of quality and reliability of Chinese-language myocardial infarction content on Bilibili and TikTok: a cross-sectional study. [PDF]
Mao Q, Zhong L, Wang S.
europepmc +1 more source
Deployable medical devices typically need external stimuli to trigger deployment. However, external stimuli are difficult to supply within tissues. Here, we describe a strategy to deploy small‐scale structures into soft tissues after insertion without the need for any stimulus. We demonstrate deployment within a tissue phantom.
Yeh‐Chia Tseng +13 more
wiley +1 more source
Scroll, Learn, Replace: Evaluating TikTok's Role in Patient Education in Total Knee Arthroplasty. [PDF]
Clark T +5 more
europepmc +1 more source

