Results 41 to 50 of about 1,349,286 (297)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Environmental Social Science and Urban Environment Management: A Review of Pathways Linking Policies and Planning to Citizens Living by the River

open access: yesQuaestiones Geographicae, 2022
Urban environment management (UEM) and environmental social science (ESS) are two interconnected approaches that show significant potential for creating more sustainable and liveable cities.
Mousazadeh Hossein
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Establishing an «Orientalium linguarum Bibliotheca» in 17th-century Vienna: Sebastian Tengnagel and the trajectories of his manuscripts

open access: yesBibliothecae.it, 2021
Sebastian Tengnagel was the court librarian of the Imperial Library in Vienna from 1608 until his death in 1636. At the same time, he was an active member of the Republic of Arabic Letters, the circle of European scholars devoted to acquiring and ...
Hülya Çelik, Chiara Petrolini
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Ortak Geçmişe Bir Armağan: Viyana Yunus Emre Çeşmesi’nin İnşa Süreci ve Mimarisi

open access: yesJournal of Literature and Humanities, 2023
Tıpkı bir insan gibi, yaşayan bir varlık olduğu düşünüldüğünde, ülkelerin çağdaşlarıyla sürekli bir ilişki içerisinde oldukları izlenmektedir. Bu ilişkiler savaş gibi negatif ya da olumsuz yönde olabilmekte veya karşılıklı iyimser politikalar üzerine ...
Gülferi Akın Ertek
doaj   +1 more source

Vienna Restaurants, Atlantic City, New Jersey list and directory

open access: yes, 1955
This map is part of an advertisement for Vienna Restaurants of Atlantic City. It lists theaters, churches, and Vienna Restaurants in the Atlantic City Area.
Vienna Restaurants
core   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Design and evaluation of FEBS Education and Training Academy module – Integrating generative artificial intelligence into life‐science education

open access: yesFEBS Open Bio, EarlyView.
Life‐science educators from 14 countries redesigned their own course materials with generative AI in a three‐session, pedagogy‐first FEBS Education and Training Academy workshop built on PICRAT. Among 12 matched respondents, four more reported high confidence in each of five practical domains, and 10 of 13 reported implementing at least one idea ...
Zvonimir Mlinarić, Ali Burak Özkaya
wiley   +1 more source

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