Modeling tumor size dynamics based on real‐world electronic health records and image data in advanced melanoma patients receiving immunotherapy [PDF]
CPT: Pharmacometrics &Systems Pharmacology, Volume 12, Issue 8, Page 1170-1181, August 2023., 2023 Abstract The development of immune checkpoint inhibitors (ICIs) has revolutionized cancer therapy but only a fraction of patients benefits from this therapy. Model‐informed drug development can be used to assess prognostic and predictive clinical factors or biomarkers associated with treatment response.
Perrine Courlet +18 more
wiley +2 more sources
Re‐imagining space: Conceptualizing new psychological interventions against segregationist attitudes and behaviours [PDF]
British Journal of Social Psychology, Volume 65, Issue 2, April 2026.Abstract Drawing on theories, concepts and empirical evidence from the fields of human geography, social and environmental psychology, this paper argues for space‐based interventions as new psychological interventions aiming to address segregationist attitudes and behaviours among co‐located groups. The main premise of this argument is that engaging in
Maria Ioannou
wiley +2 more sources
Development of an HPLC–HRMS Method for the Identification and Semi‐Quantitation in River Water Samples of the Transformation Products Originated From Heterogeneous Photocatalysis of Antipsychotic Drugs [PDF]
Journal of Separation Science, Volume 48, Issue 10, October 2025.ABSTRACT The environmental occurrence of psychiatric drugs is a growing concern due to their widespread use and persistence in aquatic systems. In this study, haloperidol and aripiprazole, two commonly prescribed antipsychotic agents, were selected as model compounds to investigate their photocatalytic modification and assess the formation of ...
Elena De Rosa +6 more
wiley +2 more sources
Luigi Vietti. Attitudine creativa
FAMagazine. Ricerche e progetti sull'architettura e la città, 2019 L’articolo propone un riesame del pensiero e dell’opera di Vietti, con particolare attenzione alla produzione da lui maturata nel periodo compreso tra le due guerre mondiali. Riprendendo alcuni dei temi affrontati in seno alla propria Ricerca di Dottorato (1989-1992), facendo leva sul confronto e sullo stretto rapporto avuto con l’architetto, prima ...
Dell'Aira, Paola Veronica
openaire +3 more sources
Luigi Vietti in Costa Smeralda: l?invenzione di un vernacolo contemporaneo [PDF]
, 2020 Luigi Vietti (1903-1998) ha avuto una carriera professionale particolarmente fortunata, in gran parte dedicata a incarichi che hanno contribuito alla trasformazione del territorio italiano, legati principalmente all?architettura per le vacanze. Negli anni trenta egli ha iniziato a definire la propria posizione culturale mantenendo una certa autonomia ...
SALA, GIORGIA
openaire +4 more sources
Chelation Therapy Associated with Antioxidant Supplementation Can Decrease Oxidative Stress and Inflammation in Multiple Sclerosis: Preliminary Results [PDF]
Antioxidants, 2023 An imbalance of oxy-inflammation status has been involved in axonal damage and demyelination in multiple sclerosis (MS). The aim of this study was to investigate the efficacy of an antioxidant treatment (calcium disodium ethylenediaminetetracetic acid ...
Alessandra Vezzoli +5 more
doaj +2 more sources
Changes in the Structure of the Bacterial Community Associated With Ericaria amentacea Blades Under Disturbed Conditions [PDF]
Plant-Environment Interactions, Volume 6, Issue 5, October 2025.ABSTRACT The macroalgae of the Cystoseira sensu lato complex host a great epiphytic bacterial community that significantly guarantees several important physiological processes, especially in case of disturbance. However, no direct evidence of relevant changes in the quali‐quantitative composition of these communities under anthropic disturbance is ...
Sarah Caronni +4 more
wiley +2 more sources
Novel RAF‐directed approaches to overcome current clinical limits and block the RAS/RAF node [PDF]
Molecular Oncology, Volume 18, Issue 6, Page 1355-1377, June 2024.RAS proteins initiate the RAS–RAF–MEK–ERK signaling by promoting dimerization of RAF kinases, also active as oncoproteins. Drugs targeting BRAFV600‐like mutations (Class I) cause the paradoxical effect and resistance, and are ineffective against other classes of BRAF malignancies.
Rossella Scardaci +7 more
wiley +2 more sources
CPT Pharmacometrics Syst Pharmacol, 2023 CPT: Pharmacometrics &Systems Pharmacology, Volume 12, Issue 8, Page 1043-1046, August 2023.
wiley +2 more sources
PEComa with metastatic pulmonary embolism upon presentation: A case report [PDF]
Radiology Case ReportsBackground: Perivascular epithelioid cell tumors (PEComas) are rare mesenchymal neoplasms with an incidence of approximately 0.3 per million. They exhibit histological and immunohistochemical features that overlap with angiomyolipomas and clear cell ...
Thomas Saliba +3 more
doaj +2 more sources