Results 1 to 10 of about 120,309 (262)

The Vigil Magnetometer for Operational Space Weather Services From the Sun‐Earth L5 Point [PDF]

Space Weather
Severe space weather has the potential to cause significant socio‐economic impact and it is widely accepted that mitigating this risk requires more comprehensive observations of the Sun and heliosphere, enabling more accurate forecasting of significant ...
C M Carr
exaly   +3 more sources

Gemogenovatucel-T (Vigil): bi-shRNA plasmid-based targeted immunotherapy [PDF]

Future Oncology
John J Nemunaitis
exaly   +4 more sources

Pilot Study of Combination Gemogenovatucel-T (Vigil) and Durvalumab in Women With Relapsed BRCA-wt Triple-Negative Breast or Ovarian Cancer

Clinical Medicine Insights: Oncology, 2022
Background: Gemogenovatucel-T (Vigil) is a triple-function autologous tumor cell immunotherapy which expresses granulocyte-macrophage colony-stimulating factor and decreases expression of furin and downstream TGF-β1 and TGF-β2.
John J Nemunaitis
exaly   +2 more sources

Long-Term Follow-Up of Gemogenovatucel-T (Vigil) Survival and Molecular Signals of Immune Response in Recurrent Ovarian Cancer

Vaccines, 2021
Aim: To determine the relationship between gene expression profile (GEP) and overall survival (OS) by NanoString following treatment with Vigil. Patients and Methods: Recurrent ovarian cancer patients (n = 21) enrolled in prior clinical trials.
Rodney P Rocconi, Robert A Barrington, Gladice Wallraven   +2 more
exaly   +3 more sources

Phase 1, First‐In‐Human, Single‐/Multiple‐Ascending Dose Study of Iluzanebart in Healthy Volunteers [PDF]

Annals of Clinical and Translational Neurology
Objective To evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of iluzanebart, a fully human monoclonal antibody TREM2 (triggering receptor expressed on myeloid cells 2) agonist, after single‐ (SAD) and multiple‐ascending‐dose ...
Andreas Meier, Spyros Papapetropoulos, Andrew Marsh, Kelly Neelon, David Stiles, Ryan O'Mara, Evan A. Thackaberry, Marco Colonna, Raj Rajagovindan   +8 more
doaj   +2 more sources

Exome sequencing shows same pattern of clonal tumor mutational burden, intratumor heterogenicity and clonal neoantigen between autologous tumor and Vigil product [PDF]

Scientific Reports
Retrospective data support overall survival (OS) advantage to high clonal tumor mutation burden (cTMB), high clonal neoantigen load (cNEO) and low intratumor heterogeneity (ITH) in cancer patients who receive immunotherapy.
David Willoughby, Ernest Bognar, Laura Stanbery, Casey Nagel, Gladice Wallraven, Aman Pruthi, Nicholas Bild, Ericca Stamper, Donald Rao, Adam Walter, John Nemunaitis   +10 more
doaj   +2 more sources

Predicting conservation priority areas in Borneo for the critically endangered helmeted hornbill (Rhinoplax vigil)

Global Ecology and Conservation
The critically endangered helmeted hornbill (Rhinoplax vigil) is under threat around its Southeast Asian range due to hunting and habitat loss. Dependant on primary rainforest habitats, the species is thought to be highly sensitive to habitat disturbance.
C.E.R. Hatten, Y.Y. Hadiprakarsa, C.K.F. Lee, A. Jain, R. Kaur, A. Miller, S. Cheema, N.J. Au, S. Khalid, C. Dingle   +9 more
doaj   +2 more sources

Vigil [PDF]

Journal of General Internal Medicine, 2019
Jason Young
openalex   +3 more sources

Case Report: Marked Survival Advantage of Two Colorectal Cancer Patients with Liver Metastases Treated with Vigil and FOLFOX-6

Vaccines, 2021
Colorectal cancer is the third most diagnosed cancer in the United States. Five-year survival rates remain low and many patients will develop liver metastasis.
Vedin Barve, Ned Adams, Laura Stanbery, Luisa Manning, Staci Horvath, Gladice Wallraven, Ernest Bognar, Minal Barve, John Nemunaitis   +8 more
doaj   +1 more source

DNA analysis and validation for species identification of seized helmeted hornbill (Rhinoplax vigil) casques

Forensic Science International: Animals and Environments, 2023
Helmeted hornbills (Rhinoplax vigil, J.R. Forster, 1781) are ‘Critically Endangered’ due to illegal hunting for their casques which are carved and traded for ornamental purposes.
Chloe E.R. Hatten, Yuli S. Fitriana, Tracey-Leigh Prigge, Mohammad Irham, Hari Sutrisno, Abinawanto, Caroline Dingle   +6 more
doaj   +1 more source