Results 1 to 10 of about 110,708 (315)

Vigil

Apparatus. Film, Media and Digital Cultures of Central and Eastern Europe, 2020
Tibor Hajas's video and article.
Tibor Hajas
doaj   +3 more sources

The Vigil of Medicine [PDF]

International Journal of Medical Students, 2021
Kiersten Kelly
doaj   +5 more sources

Pilot Study of Combination Gemogenovatucel-T (Vigil) and Durvalumab in Women With Relapsed BRCA-wt Triple-Negative Breast or Ovarian Cancer

Clinical Medicine Insights: Oncology, 2022
Background: Gemogenovatucel-T (Vigil) is a triple-function autologous tumor cell immunotherapy which expresses granulocyte-macrophage colony-stimulating factor and decreases expression of furin and downstream TGF-β1 and TGF-β2.
Minal Barve, Phylicia Aaron, Luisa Manning, Ernest Bognar, Gladice Wallraven, Staci Horvath, Laura Stanbery, John Nemunaitis   +7 more
doaj   +2 more sources

Case Report: Marked Survival Advantage of Two Colorectal Cancer Patients with Liver Metastases Treated with Vigil and FOLFOX-6

Vaccines, 2021
Colorectal cancer is the third most diagnosed cancer in the United States. Five-year survival rates remain low and many patients will develop liver metastasis.
Vedin Barve, Ned Adams, Laura Stanbery, Luisa Manning, Staci Horvath, Gladice Wallraven, Ernest Bognar, Minal Barve, John Nemunaitis   +8 more
doaj   +2 more sources

Efficacy and safety of Gemogenovatucel-T (Vigil) immunotherapy for advanced ovarian carcinoma: A systematic review and meta-analysis of randomized controlled trials

Frontiers in Oncology, 2022
In recent years, many clinical trials have shown the safety and efficacy of Gemogenovatucel-T (Vigil) in the treatment of advanced OC patients. The purpose of this study was to explore the safety and efficacy of Gemogenovatucel-T (Vigil) in the first ...
Yixin Zhang, Yixin Zhang, Li Zhang, Yuli Zhao, Yuli Zhao, Sen Wang, Sen Wang, Li Feng   +7 more
doaj   +2 more sources

Pilot Study of Recurrent Ewing's Sarcoma Management with Vigil/Temozolomide/Irinotecan and Assessment of Circulating Tumor (ct) DNA. [PDF]

Clin Cancer Res, 2023
Purpose: Treatment options for recurrent or refractory Ewing's sarcoma (ES) are limited. Vigil is a novel autologous tumor cell therapy expressing bi-shRNA furin/GMCSF plasmid, which previously demonstrated monotherapy activity in advanced ES.
Anderson P, Ghisoli M, Crompton BD, Klega KS, Wexler LH, Slotkin EK, Stanbery L, Manning L, Wallraven G, Manley M, Horvath S, Bognar E, Nemunaitis J.   +12 more
europepmc   +2 more sources

Long-Term Follow-Up of Gemogenovatucel-T (Vigil) Survival and Molecular Signals of Immune Response in Recurrent Ovarian Cancer

Vaccines, 2021
Aim: To determine the relationship between gene expression profile (GEP) and overall survival (OS) by NanoString following treatment with Vigil. Patients and Methods: Recurrent ovarian cancer patients (n = 21) enrolled in prior clinical trials.
Rodney P. Rocconi, Laura Stanbery, Luciana Madeira da Silva, Robert A. Barrington, Phylicia Aaron, Luisa Manning, Staci Horvath, Gladice Wallraven, Ernest Bognar, Adam Walter, John Nemunaitis   +10 more
doaj   +2 more sources

3D engineered scaffold for large-scale Vigil immunotherapy production [PDF]

Scientific Reports
Previously, we reported successful cellular expansion of a murine colorectal carcinoma cell line (CT-26) using a three-dimensional (3D) engineered extracellular matrix (EECM) fibrillar scaffold structure.
Fabienne Kerneis, Ernest Bognar, Laura Stanbery, Seongjun Moon, Do Hoon Kim, Yuxuan Deng, Elliot Hughes, Tae-Hwa Chun, Darron Tharp, Heidi Zupanc, Chris Jay, Adam Walter, John Nemunaitis, Joerg Lahann   +13 more
doaj   +2 more sources

The Vigil [PDF]

, 2022
This is a film review of The Vigil (2021), directed by Keith ...
Goodman, Daniel Ross
core   +3 more sources

Clinical presentation and diagnosis of adult-onset leukoencephalopathy with axonal spheroids and pigmented glia: a literature analysis of case studies [PDF]

Frontiers in Neurology
IntroductionBecause adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP) is a rare, rapidly progressive, debilitating, and ultimately fatal neurodegenerative disease, a rapid and accurate diagnosis is critical.
Spyros Papapetropoulos, Jeffrey M. Gelfand, Takuya Konno, Takeshi Ikeuchi, Angela Pontius, Andreas Meier, Farid Foroutan, Zbigniew K. Wszolek   +7 more
doaj   +2 more sources