Results 91 to 100 of about 24,272 (221)

Design Optimization of a Variable Stiffness Robotic Gripper with Passive Restoration Fabricated by Multimaterial 3D Printing

Advanced Robotics Research, EarlyView.
A multimaterial robotic gripper fabricated via multimaterial 3D printing integrates conductive thermopolymer joints with flexible elastomeric components. Joule heating enables precise joint‐level stiffness modulation, enhanced by embedded temperature sensors, passive shape restoration, and active cooling, enabling versatile manipulation capabilities ...
Daniel Jee Seng Goh, Guo Liang Goh, Selvanther Sivarajan, Van Pho Nguyen, Wai Yee Yeong   +4 more
wiley   +1 more source

The Future of Research in Cognitive Robotics: Foundation Models or Developmental Cognitive Models?

Advanced Robotics Research, EarlyView.
Research in cognitive robotics founded on principles of developmental psychology and enactive cognitive science would yield what we seek in autonomous robots: the ability to perceive its environment, learn from experience, anticipate the outcome of events, act to pursue goals, and adapt to changing circumstances without resorting to training with ...
David Vernon
wiley   +1 more source

3D‐Printing Aided Rapid Prototyping of Pretensioned Tensegrity Structures for Robotic Applications

Advanced Robotics Research, EarlyView.
Printing, injection molding, and assembly (PMA) is a method for rapid prototyping mesoscale, topologically complex, and tensioned tensegrity structures. In combination with PMA method, two mold design strategies: modular mold and compact channel layout, enable efficiency and scalability for tensegrity fabrication.
Yi Sun, Jan Petrš, Omar Aloui, Dario Floreano   +3 more
wiley   +1 more source

RIG‐I Mediated Neuron‐Specific IFN Type 1 Signaling in FUS‐ALS Induces Neurodegeneration and Offers New Biomarker‐Driven Individualized Treatment Options for (FUS‐)ALS

Advanced Science, EarlyView.
Using iPSC‐derived motoneurons and postmortem tissue from FUS‐ALS patients, it is demonstrated that increased mitochondrial transcription leads to elevated cytosolic double‐stranded RNA (dsRNA) levels. This aberrant accumulation activates a RIG‐I–dependent innate immune response leading to neurodegeneration, which is amenable for FDA‐ and EMA‐approved ...
Marcel Naumann, Theresa M. Wierschin, Stefanie Kretschmer, Banaja P. Dash, Aaron Held, Andrea Salzinger, Kevin Peikert, Anže Karlek, Hannes Glaß, Dajana Großmann, René Günther, Susanne Petri, Annekathrin Rödiger, David Brenner, Francisco Pan‐Montojo, Eleonora Aronica, Markus Kipp, Vitaly Zimyanin, Jared Sterneckert, Torsten Grehl, Noah D. Seebacher, Tobias M. Böckers, Alberto Catanese, Brian J. Wainger, Patrick Oeckl, Min Ae Lee‐Kirsch, Andreas Hermann   +26 more
wiley   +1 more source

Gender Sensitivity in Situational Risk Assessment and Risk Management Decisions in Intimate Partner Violence: A Vignette Study

Journal of Forensic Social Work
This study investigates if professionals’ situational risk assessment and risk management decisions in intimate partner violence (IPV) situations are influenced by gender of the assessed persons.
Wouter den Bode, Leontien de Kwaadsteniet, Paul van der Heijden   +2 more
doaj   +1 more source

Heuristically Adaptive Diffusion‐Model Evolutionary Strategy

Advanced Science, EarlyView.
Building on the mathematical equivalence between diffusion models and evolutionary algorithms, researchers demonstrate unprecedented control over evolutionary optimization through conditional diffusion. By training diffusion models to associate parameters with specific traits, they can guide evolution toward solutions exhibiting desired behaviors ...
Benedikt Hartl, Yanbo Zhang, Hananel Hazan, Michael Levin   +3 more
wiley   +1 more source

A novel experimental vignette methodology: SMART vignettes

Methodological Innovations
We motivate and present the methodology of vignette studies. The primary contribution of this paper is our proposal of a novel vignette study design: “SMART vignettes.” Our design has two notable features: the first is its use of sequential randomization,
Jane Paik Kim, Hyun-Joon Yang
doaj   +1 more source

Cohort‐Scale Spatial Autocorrelation for Tumor Prediction in Mid‐Infrared Pathology and Spatial Biomarker Discovery Using MALDI Imaging Lipidomics

Advanced Science, EarlyView.
Computational annotation of various tissue types in heterogeneous samples such as colorectal cancer liver metastasis (CRLM) using spatial autocorrelation analysis on non‐destructive mid‐infrared (MIR) imaging data enabled correlative multimodal mass spectrometry imaging (MSI) for spatial investigation of lipid tumor marker candidates. The method can be
Miriam F. Rittel, Nikolas Ebert, Denis Abu Sammour, Sebastian Graf, Björn C. Fröhlich, Emrullah Birgin, Shad A. Mohammed, Nuh N. Rahbari, Axel Wellmann, Oliver Wasenmüller, Cleo‐Aron Weis, Stefan Schmidt, Carsten Hopf   +12 more
wiley   +1 more source

Beyond CD30: Dual‐Targeting of Malignant and Regulatory T Cells by Brentuximab Vedotin Remodels the Lymphoma Microenvironment and Overcomes Resistance via BCL2 Inhibition in Mycosis Fungoides

Advanced Science, EarlyView.
Single‐cell RNA analyses of paired lesions from CD30+ mycosis fungoides patients demonstrate that brentuximab vedotin (BV) induces immunogenic cell death in both CD30+ and CD30− malignant T cells. BV also targets regulatory T cells and remodels tumor microenvironment, while resistance is driven by impaired IFN responses, drug efflux, and BCL2 ...
Yi Jiang, Pan Lai, Mingjia Li, Yujie Wen, Mengzhou Cao, Yu Xiao, Zhuojing Chen, Jingru Sun, Yang Wang   +8 more
wiley   +1 more source

Photon‐Sphere Modes in Curved Optical Microcavities: A Black‐Hole Analogue Laser

Advanced Science, EarlyView.
An optical analogue of a Schwarzschild black hole is realized using curved microcavities that preserve light‐like geodesics. A new family of laser modes confined around the photon sphere is identified alongside conventional whispering‐gallery modes. Analytical theory, numerical simulations, and experiments reveal curvature‐induced confinement, enabling
Chenni Xu, Aswathy Sundaresan, Nazire‐Begüm Kazkal, Clement Lafargue, Lior Zarfaty, Li‐Gang Wang, Ofek Birnholtz, Dominique Decanini, Melanie Lebental, Patrick Sebbah   +9 more
wiley   +1 more source