Results 41 to 50 of about 48,172 (238)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Alternative method of sowing canola hybrids using adhesive tape

open access: yesRevista Ceres, 2019
Canola, which has tiny oil-producing seeds, requires care during planting, so that there is an ideal number of plants. The aim of this study is to evaluate alternative method of sowing using adhesive tape and the influence it has on the emergence and ...
Raissa Macedo Assis   +5 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

PROTOCOL: Employee work motivation, effort, and performance under a merit pay system: A systematic review

open access: yesCampbell Systematic Reviews
This is the protocol for a Campbell systematic review. The objectives are as follows: One goal of this systematic review is to identify whether merit pay predicts employee work motivation, effort, and performance; a second goal is to determine whether ...
Cédric Velghe   +4 more
doaj   +1 more source

Physiological quality and aflatoxin presence in wheat seeds treated with fungicides and adjuvants during crop development

open access: yesBioscience Journal, 2019
Wheat (Triticum aestivum L.) is a cereal with great economic importance and yield capacity. However, it can be attacked by various diseases, which require the use of fungicides during crop development. Thus, this study aimed to evaluate the physiological
Lúcia Helena Pereira Nóbrega   +5 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

QUALIDADE FÍSICA, FISIOLÓGICA, SANITÁRIA E TRANSMISSÃO DE PATÓGENOS EM SEMENTES DE CANOLA

open access: yesColloquium Agrariae, 2018
A utilização de sementes com bom potencial fisiológico e sanitário garante no início do desenvolvimento da cultura um estande de plântulas adequadas que consequentemente poderá levar a bons níveis de produtividade e qualidade das lavouras.
Patricia Migliorini   +7 more
doaj   +2 more sources

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