Results 51 to 60 of about 52,710 (265)
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Frontiers in Plant ScienceMalus sieversii, a Tertiary relict and primary progenitor of the cultivated apple, is experiencing severe habitat degradation in China’s Tianshan Mountains.
Chen-Quan Gu +14 more
doaj +1 more source
Vigor e germinação de sementes híbridas de pimenteiras ornamentais
Ornamental Horticulture, 2011 Sementes híbridas nem sempre possuem bom vigor e germinação, principalmente quando são resultantes de cruzamentos interespecíficos. Nesse sentido, o objetivo desse trabalho foi avaliar o vigor e a germinação de sementes híbridas de pimenteiras ...
Mayana F. Nascimento +4 more
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FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Vigor-S, a new system for evaluating the physiological potential of maize seeds
Scientia Agricola: The refinement of vigor tests and the possibility of utilizing computer resources for the effective evaluation of the seed physiological potential have attracted considerable interest from research and seed technologists.
Danielle Otte Carrara Castan +2 more
doaj +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Revista Brasileira de Engenharia Agrícola e Ambiental, 2010 A radiação gama, proveniente da fonte de 60Co, é bastante utilizada para esterilização, visando a prevenção da decomposição e a toxidez de origem microbiana em diversos produtos.
Tatiana da S. Santos +4 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Bioscience Journal, 2009 Sementes de soja com diferentes níveis de vigor, tratadas e não tratadas com fungicida foram submetidas ao teste de germinação nos substratos areia e rolo de papel e ao teste de sanidade. No teste de germinação só houve diferenças significativas entre os
Delineide Pereira Gomes +4 more
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