Results 191 to 200 of about 439,125 (300)

Rethinking social capital in wildfire resilience: the case of central Portugal. [PDF]

Disasters
Fachada C, Mendes JM.
europepmc   +1 more source

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

Advanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters, Lorenzo Signorelli, Christian Herff, Sophia Gimple, Renzo Riemens, Gunter Kenis, Kim Rijkers, Hamed Shabani, Jyh‐Jang Sun, Yasin Temel, Hans Clusmann, Danijela Gregurec, Sarah‐Anna Hescham   +12 more
wiley   +1 more source

Businessmen-driven village governance: A viable path for rural collective economic development? [PDF]

PLoS One
Yi Y, Chen F, Yuan L, Liu C, Hu Y, Zhao Y.   +5 more
europepmc   +1 more source

Covalent Reprogramming of Kinase Binders to Modulate Protein Abundance

Advanced Science, EarlyView.
Electrophilic remodeling of a broad‐spectrum kinase binder reveals how subtle chemical changes reprogram protein fate. An acrylamide analog of a multi‐kinase binder selectively stabilizes Aurora kinase A (AURKA) by suppressing its ubiquitination, while a short‐linker variant converts this stabilizer into a degrader.
Chen Mozes, Xiaokang Jin, Miguel A. Campos, Chen Zhou, Xiaoyu Zhang   +4 more
wiley   +1 more source

Caregiver and healthcare professional perspectives on drivers of routine immunisation uptake in East New Britain, Papua New Guinea: a qualitative study. [PDF]

BMJ Public Health
Dalton M, Pomat W, Sanderson B, Melepia P, James HA, Burangat D, Duwaba L, Willie D, Paivu B, Kiromat P, Stanley E, Waramin E, Laman M, Walker S, Homer C, Robinson LJ, Scoullar MJL, Vaccher S, Danchin M.   +18 more
europepmc   +1 more source

Scalable Engineering of Bio‐Manufactured Extracellular Vesicles for Selective Delivery in Ovarian Cancer Patient‐Derived Models

Advanced Science, EarlyView.
Engineered extracellular vesicles displaying Ephrin‐B2 selectively target Ephrin‐B4–expressing ovarian cancer cells, enabling precise delivery in patient‐derived models. This scalable bio‐manufacturing platform reveals a versatile strategy to exploit Ephrin signaling for highly specific therapeutic payload delivery and motivates exploration of tailored
Nihar Godbole, Andrew Lai, Alexander Quinn, Marianne Gillard, Dominic Guanzon, Katherin Scholz‐Romero, Alexis Salas‐Burgos, Bastián Lillo Dapremont, Rohan Lourie, Naven Chetty, Richard Lobb, Kate Beecher, Amy E. McCart Reed, Kaltin Ferguson, Biao Sun, Yaowu He, John D. Hooper, Carlos Salomon   +17 more
wiley   +1 more source

Endogenesis and empowerment: logic, practical mechanism and sustainable path of rural minor pension institutions -based on the qualitative study of four villages in the Midwest of China. [PDF]

Front Public Health
Fan P, Fa R, Wang C.
europepmc   +1 more source

A High‐Throughput Live Imaging Platform to Investigate Circuit‐Dependent Regulation of Circadian Rhythms in Brain Tissue

Advanced Science, EarlyView.
Biological rhythms coordinate physiology, from genes to behavior. Study of circadian rhythms in brain tissue is constrained by limited throughput and spatial and temporal information quality. A new platform for high‐throughput, long‐term multiplexed fluorescent live imaging of circadian rhythms in brain slices is introduced.
Marco Ferrari, Natalie Ness, Julieta Acosta, Marco Brancaccio   +3 more
wiley   +1 more source

THE EFFECT OF VILLAGE FUNDS AND SPECIAL AUTONOMY FUNDS ON POVERTY IN WEST PAPUA PROVINCE

Jurnal Ekonomi dan Bisnis Airlangga
Introduction: Poverty is still a significant obstacle to development in Indonesia. To overcome this, fiscal policy through Village Funds is provided to all regions of Indonesia, including West Papua Province.
Maman Kurniawan Syahputra Silaban, Nunung Nuryartono, Eka Intan Kumala Putri   +2 more
doaj  

Toxicological Assessment of Trace Element Exposure in Relation to Sudden Unexplained Death (SUD): Environmental Geochemistry and Dietary Risk in Central-Eastern Yunnan, China. [PDF]

Toxics
Han Y, Hao L, Zhang S, Luo K.
europepmc   +1 more source