Results 141 to 150 of about 247,856 (291)

Kompetensi Kepala Desa dalam Penyelenggaraan Pemerintahan di Desa Tounelet Kecamatan Kakas Kabupaten Minahasa [PDF]

, 2017
The implementation of village governance requires more optimal handling on the aspect of RuralApparatus Human Resources, in improving the competence of village head and village apparatus. In termsof management, it is necessary to increase the capacity of
Dengo, S. (Salmin), KUENGO, S. (SYAHRUL), Posumah, J. H. (Johnny)   +2 more
core  

The Osteoblastic Microenvironment Determines the Fate of Breast Cancer Cells Disseminated in the Bone Marrow

Advanced Science, EarlyView.
This study revealed how the osteoblastic microenvironment determines the fate of cancer cells disseminated in bone, with a focus on whether they colonize, reside in quiescence, or reactivate from dormancy. Targeting integrin signaling may offer promising strategies for preventing quiescent cancer cells reactivation and bone colonization.
Hong‐Li Wang, Rui Zhang, Xiao‐Min Yue, Jie Zhou, Yu‐Fan Huang, Rong Meng, Yu‐Li Wang, Xiao‐Qing Li   +7 more
wiley   +1 more source

Empowering Local Creators and Governance for Sustainable Village Tourism in Bandung Regency

Society
Bandung Regency Regional Regulation Number 7 of 2020 regarding the development of 100 tourism villages does not explicitly regulate the governance mechanism of tourism villages.
Fery Wijayanto, Lala M. Kolopaking, Rina Mardiana   +2 more
doaj   +1 more source

Smooth the Dying Pillow: Alaska Natives and Their Destruction [original paper] [PDF]

, 1988
A slightly revised version of this paper was published as: Conn, Stephen. (1990). "Smooth the Dying Pillow: Alaska Natives and Their Destruction." Law & Anthropology: Internationales Jahrbuch für Rechtsanthropologie [International Yearbook for Legal
Conn, Stephen
core  

CHB‐Induced Immune Zonation Chaos Elicited LXRα‐mediated Lipid Metabolism Disorders in Kupffer Cells to Induce Cancer Stem Cell Formation

Advanced Science, EarlyView.
By profiling the spatiotemporal hepatic landscape of CHB mouse models, the originally peri‐portal localized KCs migrated to the peri‐central in a CXCL9‐CXCR3‐dependent manner, facilitating their interaction with HBV+ hepatocytes. The interaction promoted LMD in KCs through ASGR1‐induced LXRα degradation, which, in turn, induced CSC formation via Stat3 ...
Jingqi Shi, Qingyu Li, Jian Li, Jian Bai, Ji Xi, Qi He, Jianglin Zhou, Xuejun Wang, Xiang Song, Xiaoju Li, Xiangpei Yue, Xiaochang Zhang, Zhen Sun, Jiangbo Li, Wen Yang, Yuke Cui, Wenjie Shu, Liang Guo, Shengqi Wang   +18 more
wiley   +1 more source

A Hydrodynamic Bioreactor for High‐Yield Production of Extracellular Vesicles from Stem Cell Spheroids with Defined Cargo Profiling

Advanced Science, EarlyView.
This study harnesses hydrodynamic flows to generate, confine and stimulate stem cell spheroids, enabling the large‐scale production of extracellular vesicles (EVs). This innovative method not only streamlines spheroid formation and subsequent EV release in a single, integrated process, but also ensures the generation of EVs with enhanced biological ...
Solène Lenoir, Elliot Thouvenot, Giacomo Gropplero, Léonie Dec, Damarys Loew, Clotilde Théry, Jose E Perez, Claire Wilhelm   +7 more
wiley   +1 more source

Marine Managed Areas: What, Why, and Where [PDF]

, 2010
This paper, which focuses on ocean and coastal areas, explores the challenge of public participation by discussing the role of communities in IM. It draws on a decade of collaboration between academics and community partners to outline the community ...
Giselle Samonte-Tan, John Tschirky, Leah Bunce Karrer, Les Kaufman, Michael Orbach   +4 more
core  

Rapid Microfluidic Drug Sensitivity Testing Within 5 Days Using Minimal Clinical Tumor Samples

Advanced Science, EarlyView.
This study develops the air‐punched fabrication approach for nanoliter‐scale microcavity arrays with ultra‐smooth microcavity surfaces, with which rapid formation and 3D culture of tumor cell spheroids from small numbers of cell samples, as well as high‐throughput drug sensitivity testing can be achieved within 5 days.
Yi‐Xue Chen, Yi Zhang, Yu‐Jie Yan, Meng‐Ting Zhang, Jian‐Bo Chen, Yi‐Rong Jiang, Jie Wu, Hui‐Feng Wang, Jian‐Zhang Pan, Zhi‐Gang Chen, Jian Huang, Qun Fang   +11 more
wiley   +1 more source

Neoliberal governance, sustainable development and local communities in the Barents Region [PDF]

, 2014
There are currently high hopes in the Barents Region for economic growth, higher employment and improved well-being, encouraged by developments in the energy industry, tourism and mining.
Ejdemo, Thomas, Espiritu, Aileen A., Fors, Bjarge Schwenke, Korchak, Elena, Nosova, Tatiana, Riabova, Larissa, Tennberg, Monica, Tonkova, Elena, Vola, Joonas   +8 more
core   +2 more sources

Transplantation of GABAergic Interneuron Progenitors Restores Cortical Circuit Function in an Alzheimer's Disease Mouse Model

Advanced Science, EarlyView.
Transplantation of medial ganglionic eminence (MGE) interneuron progenitors into APP/PS1 cortices restored the slow oscillation characteristic of Alzheimer's disease. Donor cells survived, migrated, and matured into functional GABAergic interneurons, forming synaptic connections.
Shinya Yokomizo, Megi Maci, April M. Stafford, Morgan R. Miller, Stephen J. Perle, Shuzo Inagaki, Shusaku Takahashi, Heather Brown‐Harding, Linda Liang, Alex Lovely, Moustafa Algamal, Rebecca L. Gillani, Theodore J. Zwang, Douglas Richardson, Janice R. Naegele, Daniel Vogt, Ksenia V. Kastanenka   +16 more
wiley   +1 more source