Results 31 to 40 of about 3,657,706 (310)
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Village Institutional Transformation to Smart Village Governance in Tourism Village Development
Jurnal Public Policy, 2022 Institutional transformation is one of the main keys to realizing Smart Village. A Smart village cannot be separated from technology, in realizing Smart Village there are several things that must be fulfilled, namely: institutions, resources, service chains, service delivery technologies, and mechanics. This research is qualitative research with a case
Siti Anggraheni +2 more
openaire +2 more sources
Ethical Foreground and Background in Adult Educator Work
New Directions for Adult and Continuing Education, EarlyView.ABSTRACT Adult educators work in a complex ethical environment. The very act of contributing to the learning of another is fraught with moral overtones. In this paper we consider the ethical dimensions of adult educator practice by distinguishing the ethical features of the context or ‘background’ of practice from the ethical capabilities and decision ...
Steven Hodge, Sonal Nakar
wiley +1 more source
SHS Web of Conferences, 2018 This research focused on the implementation of personality principle, it is one of the basic principles in making agreement. The object of study happened in lease agreement between lessee of shop building (ruko) and operator (PB.
Sanjaya Umar Haris, Kuswara Tedy
doaj +1 more source
Village Government Readiness Toward the Adoption of E-Government
Buana Information Technology and Computer Sciences, 2023 Public services in the village are very important because the village is the smallest part of the administrative government system in Indonesia and is the front line of public services. Technological developments encourage the government to manage public
Rini Mayasari +2 more
doaj +1 more source
Jurnal Public Policy, 2023 Policy innovations made by the Cikolelet Village Government to become a tourist village and various village development efforts are efforts to overcome various problems faced by the village government and the community. The policy innovation is to change from underdeveloped villages to developing and advanced villages in 2021 according to the Village ...
Rahmawati Rahmawati +3 more
openaire +2 more sources
Implementasi E-Government dalam Pengembangan Tata Kelola Smart Village di Desa Rante Mario Kecamatan Tommo Kabupaten Mamuju [PDF]
, 2023 This research aims to understand the implementation of E-Government in Smart Village Governance in Rante Mario Village, Tommo District, Mamuju Regency. The type of research used is qualitative.
Mustari, Nuryanti +2 more
core
Structure‐Guided Dynamical Mechanics in Bioinspired Double Twisted Laminated Thin Films
Advanced Functional Materials, EarlyView.This work explores a dynamic mechanistic study of crack propagation and puncture testing via real‐time monitoring of crack initiation, propagation, and termination through nature‐inspired single and double twisted architectures fabricated from cellulose nanocrystals.
Justin Brackenridge +4 more
wiley +1 more source