Results 191 to 200 of about 18,149 (207)

Vinca Alkaloids as Chemotherapeutic Agents Against Breast Cancer

Discovery and Development of Anti-Breast Cancer Agents from Natural Products, 2021
Worldwide, breast cancer is the second most common cancer after lung cancer and it is the first most incident and prevalent cancer in women. Plant-derived natural products have historically been in drug discovery process as a source of chemotherapeutic ...
E. González-Burgos, M. Gómez-Serranillos   +1 more
semanticscholar   +1 more source

Vinca alkaloids and analogues as anti-cancer agents: Looking back, peering ahead.

Bioorganic & Medicinal Chemistry Letters, 2018
Cancer still represents a "nightmare" worldwide, causing annually millions of victims. Several antiproliferative molecules are currently used as drugs market and offer a pharmaceutical opportunity for attenuating and treating tumor manifestations.
E. Martino, G. Casamassima, S. Castiglione, E. Cellupica, Serena Pantalone, Francesca Papagni, Marta Rui, A. Siciliano, S. Collina   +8 more
semanticscholar   +1 more source

Extraction of bioactive compounds from Catharanthus roseus and Vinca minor

Separation and Purification Technology, 2020
The aim of this study was to extract and identify the major constituents, namely, the indole alkaloids, from two Apocynaceae medicinal plant family species, Catharanthus roseus and Vinca minor when using different solvents (the alcohol mixtures, the ...
M. Koel, Maria Kuhtinskaja, M. Vaher
semanticscholar   +1 more source

Anti-tubulin agents of natural origin: Targeting taxol, vinca, and colchicine binding domains.

European journal of medicinal chemistry, 2019
Microtubules are a protein which is made of α- and β-heterodimer. It is one of the main components of the cell which play a vital role in cell division especially in G2/M-phase. It exists in equilibrium dynamic of polymerization and depolymerization of α-
Fatima Naaz, M. R. Haider, S. Shafi, M. S. Yar   +3 more
semanticscholar   +1 more source

Vinca alkaloids, thalidomide and eribulin‐induced peripheral neurotoxicity: From pathogenesis to treatment

Journal of the peripheral nervous system, 2019
Vinca alkaloids, thalidomide, and eribulin are widely used to treat patients with childhood acute lymphoblastic leukemia (ALL), adults affected by multiple myeloma and locally invasive or metastatic breast cancer, respectively.
Badrul Islam, Maryam Lustberg, N. Staff, N. Kolb, P. Alberti, A. Argyriou   +5 more
semanticscholar   +1 more source

Effect of Vinca Alkaloids on the Expression Levels of microRNAs Targeting Apoptosis-related Genes in Breast Cancer Cell Lines.

Current Pharmaceutical Biotechnology, 2019
BACKGROUND Treatment of cancer with natural chemotherapeutic agents induces apoptosis along with remarkable alterations in the expression of apoptosis-related genes. Deregulation of microRNA (miRNA) expression is implicated in several human malignancies.
Adamantios V. Mavrogiannis, Ioanna Kokkinopoulou, C. Kontos, D. Sideris   +3 more
semanticscholar   +1 more source

Observations on the origin and demography of the Vinča culture

, 2020
The Vinca culture represents one the most important archaeological phenomena of the Neolithic and Eneolithic world in Southeastern Europe. As all other archaeological cultures, the Vinca culture is defined in the era of culture-historical archaeology ...
M. Porčić
semanticscholar   +1 more source

Green Synthesis of ZnO and V-Doped ZnO Nanoparticles Using Vinca rosea Plant Leaf for Biomedical Applications

Applied Biochemistry and Biotechnology, 2023
Senthilkumar Chandrasekaran, V. Anbazhagan   +1 more
semanticscholar   +1 more source

Application of Bacillus megaterium MCR-8 improved phytoextraction and stress alleviation of nickel in Vinca rosea

International journal of phytoremediation, 2017
Waheed Ullah Khan, S. Ahmad, Nasim Ahmad Yasin, Aamir Ali, Aqeel Ahmad, Waheed Akram   +5 more
semanticscholar   +1 more source