Results 71 to 80 of about 11,303 (160)

Mechanisms of spinal glial activation in chemotherapy‐induced peripheral neuropathy: Focus on microglia and astrocytes

Ibrain, Volume 12, Issue 1, Page 65-85, Spring 2026.
Chemotherapy‐induced peripheral neuropathy (CIPN) remains a major clinical challenge, with central sensitization considered an important pathological mechanism in its occurrence and persistence. This review focuses on spinal astrocytes and microglia, systematically summarizing the pathological mechanisms of spinal glial cells involved in CIPN caused by
Long Gu, Song Cao, Yonghuai Feng
wiley   +1 more source

Vinca alkaloids as a potential cancer therapeutics: recent update and future challenges

3 Biotech, 2023
Aditya Banyal, Shubham Tiwari, Aparajita Sharma, Ishita Chanana, S. S. Patel, S. Kulshrestha, Pradeep Kumar   +6 more
semanticscholar   +1 more source

Modulatory Effects of Cirsimarin on Lung Cancer A549 Cells Migration in 2D and 3D Cultures Involves Transcriptional Regulation of Metalloproteinases

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 3, March 2026.
In 2D culture, the cirsimarin (i) decreased cell viability in both assays, (ii) induced apoptosis, (iii) reduced clonogenicity, (iv) prevented cell migration, (v) induced DNA damage, and (vi) negatively modulated gene expression. In the 3D model, reductions in spheroid viability, area, and cell migration were also observed.
Anna Gabriele Prado dos Santos, Celina Yung‐Ai Lin Lee, Érica Romão Pereira, Andresa Hiromi Sakai, Diego Luís Ribeiro, Victor Antônio Silva Lima, Marcos Bispo Pinheiro Camara, Cláudia Quintino da Rocha, Sabine A. S. Langie, Ilce Mara de Syllos Cólus, Juliana Mara Serpeloni   +10 more
wiley   +1 more source

Society for Maternal‐Fetal Medicine Consult Series #76: Cancer in pregnancy

Pregnancy, Volume 2, Issue 2, March 2026.
Abstract Approximately one in 1000 pregnancies is complicated by the diagnosis of cancer each year, and the incidence of cancer among reproductive‐age individuals is increasing. Management of a pregnant person with cancer can be complex and warrants a multidisciplinary approach to care.
Society for Maternal‐Fetal Medicine (SMFM), Moti Gulersen, Clarissa Bonanno, Justin S. Brandt, Stephanie Pierce, Elyce H. Cardonick, SMFM Publications Committee   +6 more
wiley   +1 more source

The ERK–ZEB1 pathway mediates epithelial–mesenchymal transition in pemetrexed resistant lung cancer cells with suppression by vinca alkaloids

Oncogene, 2016
High thymidylate synthase (TS) level in cancer tissue is considered to result in resistance to pemetrexed therapy for advanced stages of nonsquamous non-small cell lung cancers.
Chi Ly, Hsin Il, Yang Ty, W. Sung, Chien Jy, J. Chang, J. Ko, G. Sheu   +7 more
semanticscholar   +1 more source

Climate Impacts in Scenarios: Time to Close the Loop?

Earth's Future, Volume 14, Issue 3, March 2026.
Abstract Integrated modeling of Earth and human systems, accounting for feedbacks, is key to fully understand climate change consequences and ensuing adaptation needs. In some aspects of climate research, however, closing this loop has proved particularly challenging.
Claudia Tebaldi, Brian O'Neill, Edward Byers   +2 more
wiley   +1 more source

The Invention of tradition: Vinča script

Etnoantropološki Problemi, 2016
The problematic term the Vinča script denotes a number of incised ornaments and signs on the surface of the pottery of the Vinča culture – one of the most important "cultures" of the South Eastern European Neolithic.
Aleksandar Palavestra
doaj  

Development and Testing of an Owner‐Reported Outcome Measure of Clinical Signs and Quality of Life in Dogs Treated With Chemotherapy

Veterinary and Comparative Oncology, Volume 24, Issue 1, Page 80-94, March 2026.
ABSTRACT Cancer is a leading cause of mortality in older dogs. Despite the prevalence of chemotherapy in canine oncology, a good understanding of owners' observations of side effects and clinical signs in real time is still lacking. Owners' perceptions and reporting of clinical signs play an important role in monitoring a dog's condition during ...
Jenny Harris, Katie Sutton, Quentin Fournier, Jo Armes, Emma Ream, Nicholas Bacon   +5 more
wiley   +1 more source

The First Global Report on the Alkaloid Aspidospermidine in Vinca herbacea: A Potential Source of Anticancer Alkaloid Precursors

Future Natural Products
Vinca herbacea Waldst. & Kit., a rare perennial species of the Apocynaceae family, is distributed across temperate regions of Western Asia and Eastern Europe. However, its presence in Iran is restricted to a few recorded sites.
Mohammad Kordkatouli, Aryan Sateei
doaj   +1 more source

Antimicrobial effect of active carbonaceous material obtained by hydrothermal carbonization of fructose

Zaštita Materijala, 2017
Activated carbons due to their antimicrobial effect have been used in medicine for a long period of time. The active carbon material is obtained at a temperature of 260°C, by hydrothermal carbonization of fructose in the presence of phosphoric acid.
Branka Kaluđerović, Vesna Mandušić, Đuro Čokeša, Vladimir Dodevski, Sanja Krstić, Jelena Hranisavljević, Srđan Milanović   +6 more
doaj   +1 more source