Results 51 to 60 of about 2,054 (182)

Design, Synthesis, Cytotoxicity Assessment, and Molecular Docking of Novel Triazolopyrimidines as Potent Cyclin‐Dependent Kinase 4 Inhibitors

ChemistryOpen, Volume 15, Issue 4, April 2026.
A novel series of 1,5‐dihydro‐[1,2,4]triazolo[4,3‐a]pyrimidines (5a–g) is synthesized and evaluated as potential CDK4 inhibitors. Compounds 5c and 5d exhibit strong cytotoxicity toward HepG2 and MCF‐7 cells with IC50 ≈ 1–2 µM, comparable to doxorubicin.
Tariq Z. Abolibda, Sami A. Al‐Hussain, Basant Farag, Mohamed El‐Naggar, Magdi E. A. Zaki, Emad S. A. Alhazmi, Adel S. M. Almohammadi, Sobhi M. Gomha   +7 more
wiley   +1 more source

Molecular Studies on the Effects of Auxins and Cytokinins on Vinca Rosae, Grown by Plant Tissue Culture

Scientific Journal of King Faisal University: Basic and Applied Sciences, 2020
Vinca Rosea (Apocynacea) is an important medicinal plant. In this study, the tissue culture propagation of vinca, using explants from stems and leaves, was investigated.
Sumayah I. Alsanie, Mohey Elden K. Beharry, Mona S. Alahmadi   +2 more
doaj   +1 more source

Early Life Conditions and Physiological Stress following the Transition to Farming in Central/Southeast Europe: Skeletal Growth Impairment and 6000 Years of Gradual Recovery. [PDF]

, 2016
Early life conditions play an important role in determining adult body size. In particular, childhood malnutrition and disease can elicit growth delays and affect adult body size if severe or prolonged enough.
Macintosh, Alison A, Pinhasi, Ron, Stock, Jay T   +2 more
core   +3 more sources

Managing Skin Side Effects Associated With Oncology Treatments: Asian Perspective on Use of Dermocosmetics

Asia-Pacific Journal of Clinical Oncology, Volume 22, Issue 2, Page 186-198, April 2026.
Skin adverse events (AEs) frequently accompany all types of anticancer treatments. This publication discusses how recent international guidance on best‐practices use of dermocosmetics can be adapted to the North Asia region (China, Hong Kong, Japan, Republic of Korea, and Taiwan).
Meng Pan, Jianguo Sun, Makoto Kawashima, You Chan Kim, Mison Chun, Chia‐Yu Chu, Yi‐Hsin Liang, Mee Chang, Delphine Kerob, Brigitte Dreno   +9 more
wiley   +1 more source

Neolitikus kultúrák kapcsolatrendszere kerámia vizsgálaton keresztül = Understanding the relationship between Neolithic communities through ceramic analysis [PDF]

, 2012
A pályázat keretében összesen 13 lelőhelyről vizsgáltuk Starčevo, Körös, Vinča, AVK, DVK, Zseliz és Lengyel kultúrák kerámiatechnológiáit. A vizsgálatok során összesen 598 db vékonycsiszolatot készítettünk.
Bánffy, Eszter, Eke, István, Kalicz, Nándor, Kreiter, Attila, Szakmány, György   +4 more
core  

Modulatory Effects of Cirsimarin on Lung Cancer A549 Cells Migration in 2D and 3D Cultures Involves Transcriptional Regulation of Metalloproteinases

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 3, March 2026.
In 2D culture, the cirsimarin (i) decreased cell viability in both assays, (ii) induced apoptosis, (iii) reduced clonogenicity, (iv) prevented cell migration, (v) induced DNA damage, and (vi) negatively modulated gene expression. In the 3D model, reductions in spheroid viability, area, and cell migration were also observed.
Anna Gabriele Prado dos Santos, Celina Yung‐Ai Lin Lee, Érica Romão Pereira, Andresa Hiromi Sakai, Diego Luís Ribeiro, Victor Antônio Silva Lima, Marcos Bispo Pinheiro Camara, Cláudia Quintino da Rocha, Sabine A. S. Langie, Ilce Mara de Syllos Cólus, Juliana Mara Serpeloni   +10 more
wiley   +1 more source

An overview of the knapped stone economy at the Tărtăria site (Romania)

Journal of Lithic Studies, 2016
This study focused on sourcing the lithic artefacts from the Tărtăria site in the Transylvanian Basin. The objective was to establish a model of the procurement patterns of the population at the settlement. This site is located along the middle region of
Otis Crandell
doaj   +1 more source

Late neolithic pottery standardization: Application of statistical analyses [PDF]

Starinar, 2011
This paper defines the notion of standardization, presents the methodological approach to analysis, points to the problems and limitation arising in examination of materials from archaeological excavations, and presents the results of the ...
Vuković Jasna
doaj   +1 more source

In Vitro Cytotoxicity Assessment of Leaves of Tieghemella heckelii on Breast (MDA‐MB‐468), Liver (HepG2), and Prostate (PC3) Cancer Cell Lines

BioMed Research International, Volume 2026, Issue 1, 2026.
Introduction Cancer remains the leading cause of death worldwide, with breast cancer being the most prevalent disease diagnosed globally. Liver cancer is the fourth most common cause of death globally, while prostate cancer accounts for the second most frequent malignancy among males worldwide.
Justice Kumi, Abigail Aning, Janet Ampofo, Sherif Hamidu, Eric N. Y. Nyarko, Poorani Gurumallesh Prabu   +5 more
wiley   +1 more source

Stone tools from locality Crkvine in Stubline [PDF]

Starinar, 2011
Stone artifacts from excavations in Crkvine in 2008. originate from two stratigraphic units, both chronologically defined as the final stage of the Vinča culture: 1. distruction layer above and 2. from the floor of House 1/2008.
Antonović Dragana, Šarić Josip
doaj   +1 more source