Results 51 to 60 of about 303 (138)

Biopharmaceuticals for Cancer Treatment: An Update

Cancer Medicine, Volume 15, Issue 4, April 2026.
ABSTRACT Cancer is one of the most debilitating diseases, causing profound physical and psychological impacts on patients. The global number of cancer patients has been steadily rising over the last few decades. The development of effective cancer therapies remains the primary focus in life science research, requiring a precise understanding of ...
Anupom Deb Nath, Yousuf Alam, Afsana Mustak Mim, Maksuda Akter, Mohammad Abbas Gani, Khondaker Muhammad Khairul Alam, Md. Nur Alam   +6 more
wiley   +1 more source

Marital Residence Patterns in Late Neolithic Communities of the Vinča Culture

Etnoantropološki Problemi, 2011
This paper aims to reconstruct the marital residence patterns in late Neolithic communities in the central Balkans. The average size of the habitation site was used as a correlate of patrilocality or matrilocality.
Marko Porčić
doaj   +1 more source

Mechanism of Gzma‐mediated GEF‐H1 activation in intestinal epithelial cells leading to intestinal barrier dysfunction in sepsis

Clinical and Translational Medicine, Volume 16, Issue 4, April 2026.
Abstract Background Sepsis‐induced intestinal injury is a severe complication associated with dysfunction affecting multiple organ systems and a significantly elevated risk of death. Intestinal barrier dysfunction plays a central role, but the underlying molecular pathways remain incompletely understood. The present study sought to explore how the Gzma/
Zexing Lin, Haiyang Jiang, Chujun Ni, Liting Deng, Huan Yang, Runnan Wang, Peizhao Liu, Xuanheng Li, Yilong Yu, Weijie Li, Bo Liao, Juanhan Liu, Weizhen Li, Jiaxin Yang, Yue Chao, Haiqing Liu, Xiuwen Wu, Jianan Ren, Yun Zhao   +18 more
wiley   +1 more source

Design, Synthesis, Cytotoxicity Assessment, and Molecular Docking of Novel Triazolopyrimidines as Potent Cyclin‐Dependent Kinase 4 Inhibitors

ChemistryOpen, Volume 15, Issue 4, April 2026.
A novel series of 1,5‐dihydro‐[1,2,4]triazolo[4,3‐a]pyrimidines (5a–g) is synthesized and evaluated as potential CDK4 inhibitors. Compounds 5c and 5d exhibit strong cytotoxicity toward HepG2 and MCF‐7 cells with IC50 ≈ 1–2 µM, comparable to doxorubicin.
Tariq Z. Abolibda, Sami A. Al‐Hussain, Basant Farag, Mohamed El‐Naggar, Magdi E. A. Zaki, Emad S. A. Alhazmi, Adel S. M. Almohammadi, Sobhi M. Gomha   +7 more
wiley   +1 more source

Acholeplasma laidlawii PG8 Culture Adapted to Unfavorable Growth Conditions Shows an Expressed Phytopathogenicity

The Scientific World Journal, 2007
Mycoplasmas are the smallest, self-replicating, prokaryotic organisms with avid biochemical potential and spreading in higher eukaryotes in nature.
Vladislav M. Chernov, Natalia E. Moukhametshina, Yurii V. Gogolev, Tatiana N. Nesterova, Maxim V. Trushin, Olga A. Chernova   +5 more
doaj   +1 more source

Spondylus and Glycymeris bracelets: trade reflections at Neolithic Vinča-Belo Brdo

Documenta Praehistorica, 2006
In the provision, production and exchange of prestigious items and materials in prehistoric Europe, marine shell ornaments play important role. The marine shell collection at the Vinča-Belo Brdo site is the largest in the central and northern Balkans ...
Vesna Dimitrijević, Boban Tripković
doaj   +1 more source

Managing Skin Side Effects Associated With Oncology Treatments: Asian Perspective on Use of Dermocosmetics

Asia-Pacific Journal of Clinical Oncology, Volume 22, Issue 2, Page 186-198, April 2026.
Skin adverse events (AEs) frequently accompany all types of anticancer treatments. This publication discusses how recent international guidance on best‐practices use of dermocosmetics can be adapted to the North Asia region (China, Hong Kong, Japan, Republic of Korea, and Taiwan).
Meng Pan, Jianguo Sun, Makoto Kawashima, You Chan Kim, Mison Chun, Chia‐Yu Chu, Yi‐Hsin Liang, Mee Chang, Delphine Kerob, Brigitte Dreno   +9 more
wiley   +1 more source

Modulatory Effects of Cirsimarin on Lung Cancer A549 Cells Migration in 2D and 3D Cultures Involves Transcriptional Regulation of Metalloproteinases

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 3, March 2026.
In 2D culture, the cirsimarin (i) decreased cell viability in both assays, (ii) induced apoptosis, (iii) reduced clonogenicity, (iv) prevented cell migration, (v) induced DNA damage, and (vi) negatively modulated gene expression. In the 3D model, reductions in spheroid viability, area, and cell migration were also observed.
Anna Gabriele Prado dos Santos, Celina Yung‐Ai Lin Lee, Érica Romão Pereira, Andresa Hiromi Sakai, Diego Luís Ribeiro, Victor Antônio Silva Lima, Marcos Bispo Pinheiro Camara, Cláudia Quintino da Rocha, Sabine A. S. Langie, Ilce Mara de Syllos Cólus, Juliana Mara Serpeloni   +10 more
wiley   +1 more source

Southwest Asian founder- and other crops at Neolithic sites in Serbia

Българско е-Списание за Археология, 2014
The paper presents the range of crops documented at Neolithic sites in the territory of Serbia and discusses the differences between early and late Neolithic crop spectra. The approximate timing of arrival to the region of the founder- and other crops is
Dragana Filipović
doaj  

The Invention of tradition: Vinča script

Etnoantropološki Problemi, 2016
The problematic term the Vinča script denotes a number of incised ornaments and signs on the surface of the pottery of the Vinča culture – one of the most important "cultures" of the South Eastern European Neolithic.
Aleksandar Palavestra
doaj