Results 121 to 130 of about 16,162 (177)
Some of the next articles are maybe not open access.
Indole Alkaloids from Vinca sardoa, a New Species of Vinca
HETEROCYCLES, 1990Four natural N-methylindolines have been isolated from the roots of Vinca sardoa (Stearn) Pignati. They are ent-N(1)-methyl-14,15-didehydroaspidospermidine (7),N(1)-methyl-14,15-didehydroaspidofractinine (10), N(1)-methylaspidofractinine (11) and N(1)-methyl-14,15-didehydrotuboxenine (13)
S. CRIPPA +5 more
openaire +2 more sources
Reduction of Toxicity of a Vinca Alkaloid by an Anti-Vinca Alkaloid Antibody
Cancer Investigation, 1995Inadvertent oncolytic overdoses occur rarely, but can have serious consequences. We have investigated the possibility of using an antibody, 27.8.1A, reactive with vinca alkaloids, as a means of reducing the toxicity associated with overdose situations.
M C, Gutowski +3 more
openaire +2 more sources
1975
The vinca alkaloids are antineoplastic indole derivatives (Fig. 1) that are isolated from the leaves of the periwinkle plant, Vinca rosea L., or more correctly, Catharanthus roseus G. Don. This plant is of Madagascan origin, although its distribution is now pantropical (Stearn, 1975).
openaire +1 more source
The vinca alkaloids are antineoplastic indole derivatives (Fig. 1) that are isolated from the leaves of the periwinkle plant, Vinca rosea L., or more correctly, Catharanthus roseus G. Don. This plant is of Madagascan origin, although its distribution is now pantropical (Stearn, 1975).
openaire +1 more source
A comparative chemotaxonomic study onVinca sardoastearn andVinca difformispourret
Natural Product Research, 2005The phytochemical analysis of iridoidic fraction of the aerial parts of Vinca sardoa and Vinca difformis, gave the identification of loganic acid in V. difformis as unique iridoid glucoside, while loganin is also present in V. sardoa. The two taxa highly differ in alkaloids, so the chemotaxonomic classification in two different species is supported.
BIANCO, Armandodoriano +7 more
openaire +4 more sources
2010
The periwinkle plant, Cantharanthus roseus G. Don (Vinca rosea Linn.) is endemic to the island of Madagascar, and has long been ascribed a wide assortment of medicinal properties ranging from the treatment of diabetes to wound healing. Of the over fifty alkaloids present in minute quantities within the plant, only two (vincristine and vinblastine) have
Nicole Coufal, Lauge Farnaes
openaire +1 more source
The periwinkle plant, Cantharanthus roseus G. Don (Vinca rosea Linn.) is endemic to the island of Madagascar, and has long been ascribed a wide assortment of medicinal properties ranging from the treatment of diabetes to wound healing. Of the over fifty alkaloids present in minute quantities within the plant, only two (vincristine and vinblastine) have
Nicole Coufal, Lauge Farnaes
openaire +1 more source
2000
Abstract Vincristine (VCR) and vinblastine (VBL), derivatives of the periwinkle plant (Vinca rosea), are important chemotherapeutic agents with similar neurotoxic actions. VCR, the subject here, is far more widely used than VBL and has Iqbal Z, Ochs S (1980) Uptake of Vinca alkaloids into mammalian nerve and its subcellular components.
openaire +1 more source
Abstract Vincristine (VCR) and vinblastine (VBL), derivatives of the periwinkle plant (Vinca rosea), are important chemotherapeutic agents with similar neurotoxic actions. VCR, the subject here, is far more widely used than VBL and has Iqbal Z, Ochs S (1980) Uptake of Vinca alkaloids into mammalian nerve and its subcellular components.
openaire +1 more source
2005
Abstract The periwinkle plant (Cantharantus roseus; Vinca rosea L.), originally indigenous to Madagascar but now cultivated all over the world, has a long and colourful history of medicinal uses for the treatment of such widely dissimilar conditions as haemorrhage, scurvy, toothache, wound healing, and diabetes.
openaire +1 more source
Abstract The periwinkle plant (Cantharantus roseus; Vinca rosea L.), originally indigenous to Madagascar but now cultivated all over the world, has a long and colourful history of medicinal uses for the treatment of such widely dissimilar conditions as haemorrhage, scurvy, toothache, wound healing, and diabetes.
openaire +1 more source