Results 121 to 130 of about 2,799,905 (389)

Men's and women's experiences of violence and traumatic events in rural Cote d'Ivoire before, during and after a period of armed conflict. [PDF]

open access: yes, 2014
OBJECTIVE: We assessed men's and women's experiences of gender based violence and other traumatic events in Côte d'Ivoire, a West African conflict-affected setting, before, during and after a period of active armed conflict (2000-2007).
Bakayoko-Topolska, Monika   +7 more
core   +2 more sources

Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?

open access: yesMolecular Oncology, EarlyView.
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley   +1 more source

Intimate Partner Violence and Sexual Violence in Bristol Bay: Key Results from the 2011 Alaska Victimization Survey [PDF]

open access: yes, 2011
This document is a two-page summary of the key results from the 2011 Alaska Victimization Survey for the Brisol Bay region, which was conducted from April to June 2011, with results released on October 12, 2011 in Dillingham. Findings include: * Over
Rosay, André B.
core  

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Intimate Partner Violence and Sexual Violence in the City and Borough of Sitka: Key Results from the 2012 Alaska Victimization Survey [PDF]

open access: yes, 2012
This document is a two-page summary of the key results from the 2012 Alaska Victimization Survey for the City and Borough of Sitka, which was conducted from March to May 2012, with results released on October 19, 2012 in Sitka. Findings include: * 47%
Rosay, André B.
core  

Violence breeds violence [PDF]

open access: yesAustralian Veterinary Journal, 2004
Mark Lawrie, Mike Bond
openaire   +2 more sources

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