Results 261 to 270 of about 2,052,059 (368)

Autologous Peripheral Vγ9Vδ2 T Cell Synergizes with αβ T Cell Through Antigen Presentation and BTN3A1 Blockade in Immunotherapy of Cervical Cancer

open access: yesAdvanced Science, EarlyView.
This study provides proof‐of‐concept evidence showing that through direct killing, antigen presentation, and competitively binding to BTN3A1, Vγ9Vδ2 T cells amplified from cervical cancer (CC) patients can synergize with αβ T cells to exert anti‐CC function both in vitro and in vivo.
Min Wu   +21 more
wiley   +1 more source

Blockade of ZMIZ1‐GATA4 Axis Regulation Restores Youthfulness to Aged Cartilage

open access: yesAdvanced Science, EarlyView.
The blockade of ZMIZ1‐GATA axis can be an effective therapeutic approach for treating OA. Functional inhibition of the ZMIZ1‐GATA axis through K‐7174 has the effect of suppressing cartilage damage and cellular senescence at the chondrocyte and cartilage tissue levels.
Jiho Nam   +8 more
wiley   +1 more source

Assessment, frequency, and reasons for child-to-parent violence in a sample of Italian adolescents. [PDF]

open access: yesSci Rep
Navas-Martínez MJ   +4 more
europepmc   +1 more source

Metabolic‐Immune Suppression Mediated by the SIRT1‐CX3CL1 Axis Induces Functional Enhancement of Regulatory T Cells in Colorectal Carcinoma

open access: yesAdvanced Science, EarlyView.
This study discovers that SIRT1, a hub gene involved in glucolipid metabolic conversion in colorectal carcinoma (CRC), stimulates CX3CL1 secretion in CRC cells by activating FOXO1. The CX3CL1‐CX3CR1 signaling promotes the differentiation of TCF7+ regulatory T cells (Tregs) into an enhanced immunosuppressive TNFRSF9+ Treg phenotype.
Ruiyang Zi   +18 more
wiley   +1 more source

Domestic violence and childhood trauma among married women using machine learning approach: a cross-sectional study. [PDF]

open access: yesBMC Public Health
Al Mutair A   +7 more
europepmc   +1 more source

FUS Selectively Facilitates circRNAs Packing into Small Extracellular Vesicles within Hypoxia Neuron

open access: yesAdvanced Science, EarlyView.
This study aimed to unravel the role of FUS in the loading of functional circRNAs into neuronal sEVs under hypoxic conditions, which involves their aggregations in SGs and specific interaction between the FUS Zf_RanBP domain to regulate circRNA sorting in sEVs.
Jiankun Zang   +14 more
wiley   +1 more source

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