Results 311 to 320 of about 2,052,059 (368)

Pinoresinol Diglucoside Attenuates Nuclear Receptor Coactivator 4‐Mediated Ferritinophagy Associated with Cisplatin‐Induced Hearing Loss

Advanced Science, EarlyView.
Pinoresinol diglucoside, a bioactive component extracted from traditional Chinese medicine, attenuates cisplatin‐induced ototoxicity in vivo and in vitro. The protective effect is achieved by downregulation of Socs1. The present study is the first to investigate the expression and function of Socs1 in inner ear, which is known to promote ferroptosis ...
Yin Chen, Cheng Cheng, Ao Li, Dengbin Ma, Siyu Li, Handong Wang, Song Gao, Dingding Liu, Panpan Song, Chenjie Yu, Xiaoyun Qian, Guoqiang Wan, Xia Gao   +12 more
wiley   +1 more source

Patterns of self-reported alcohol and drug use among children and youth: Mozambique violence against children survey (VACS) 2019. [PDF]

BMC Public Health
Semá Baltazar C, Ribeiro Banze A, Muleia R.   +2 more
europepmc   +1 more source

Award Metadata - Gun Violence Prevention and Justice Reform [PDF]

, 2019
Seattle University
core   +1 more source

Genome‐Wide Silencer Screening Reveals Key Silencer Modulating Reprogramming Efficiency in Mouse Induced Pluripotent Stem Cells

Advanced Science, EarlyView.
This study utilized Ss‐STARR‐seq to construct a genome‐wide silencer map of mouse cells and elucidated the fundamental characteristics of these silencers. These silencers exist in a cell‐specific manner and exhibit unique epigenetic modifications. Through functional experiments, we also discovered that these silencers can regulate gene expression and ...
Xiusheng Zhu, Lei Huang, Guoli Li, Biao Deng, Xiaoxiao Wang, Hu Yang, Yuanyuan Zhang, Qiuhan Wen, Chao Wang, Jingshu Zhang, Yunxiang Zhao, Kui Li, Yuwen Liu   +12 more
wiley   +1 more source

Pupils' aggressive behaviour towards teachers: identifying protective factors at organizational level examined in a follow-up study. [PDF]

BMC Psychol
Andersen LPS, Aust B, Winding TN.
europepmc   +1 more source

Reducing violence and injury in the WHO European region

The Lancet Public Health, 2020
Yongjie Yon, Lucía Hernández-García, Gianluca Di Giacomo, Ivo Rakovac, Jonathon Passmore, Bente Mikkelsen   +5 more
doaj  

AAVR Expression is Essential for AAV Vector Transduction in Sensory Hair Cells

Advanced Science, EarlyView.
Decreased sensitivity to AAV vector transduction in the outer hair cells (OHCs) of adult mice is primarily attributed to reduction of AAVR (Kiaa0319l; Au040320). Knockout of AAVR reduces AAV vector transduction efficiency in both inner hair cells (IHCs) and OHCs in neonatal mice.
Fan Wu, Guisheng Chen, Rui Hu, Peiwen Liu, Jintao Lou, Wenji Zhao, Zuhong He, Suhua Sha, Yiqing Zheng   +8 more
wiley   +1 more source

Spatial de-concentration of fatal and nonfatal firearm violence in Boston, MA, 2007-2021. [PDF]

Inj Epidemiol
Shareef F, Gause EL, McLone S, Gebo E, Jay J.   +4 more
europepmc   +1 more source

Single Administration of AAV‐mAtp6v1b2 Gene Therapy Rescues Hearing and Vestibular Disorders Caused by Atp6v1b2‐Induced Lysosomal Dysfunction in Hair Cells

Advanced Science, EarlyView.
Wei et al. establish a hair cell‐specific conditional knockout mouse model (Atp6v1b2fl/fl;Atoh1Cre/+), and demonstrate the importance of Atp6v1b2 for hair cell through maintaining the survival of lysosomes. A single administration of AAV‐ie‐Eh3‐mAtp6v1b2 through scala media at P0‐P2 realizes function compensation and restores hearing and balance ...
Gege Wei, Shiwei Qiu, Xue Gao, Lu Zheng, Yijin Chen, Ying Ma, Haifeng Feng, Jinyuan Yang, Guojie Dong, Huiyi Nie, Weihao Zhao, Xiaoge Li, Guangqin Wang, Wei Xiong, Pu Dai, Yongyi Yuan   +15 more
wiley   +1 more source

Individual-level deviations from normative brain morphology in violence, psychosis, and psychopathy. [PDF]

Transl Psychiatry
Haukvik UK, Wolfers T, Tesli N, Bell C, Hjell G, Fischer-Vieler T, Bang N, Melle I, Andreassen OA, Rasmussen K, Agartz I, Westlye LT, Friestad C, Rokicki J.   +13 more
europepmc   +1 more source