Artesunate Inhibits Neointimal Hyperplasia by Promoting IRF4 Associated Macrophage Polarization
This study shows that macrophage interferon regulatory factor 4 (IRF4) improved arterial injury‐induced neointimal hyperplasia by promoting of M2 polarization via up‐regulating krüppel‐like factor 4 (KLF4) in rodent and nonhuman primate models. Notably, artesunate is identified as a potent inducer of IRF4 in macrophages, and proposed as a promising ...
Jinlin Miao+15 more
wiley +1 more source
Measuring real-time violence exposure and its impact on intimate partner violence perpetration among adolescents. [PDF]
Kidman R+7 more
europepmc +1 more source
α‐Synuclein Pathology Spreads in a Midbrain–Hindbrain Assembloid Model
A novel midbrain–hindbrain assembloid model demonstrates the spread of α‐synuclein pathology, a hallmark of Parkinson's disease, mimicking Braak's hypothesis. This model reveals how pathology propagates from the hindbrain to the midbrain, inducing synaptic changes and early signs of neuronal vulnerability. It offers an innovative platform for exploring
Gemma Gomez‐Giro+14 more
wiley +1 more source
Corrigendum: Dating violence in Portugal: how can it be handled in secondary schools and universities? [PDF]
Neves S, Correia A.
europepmc +1 more source
This study presents a novel approach for treating Duchenne muscular dystrophy using mRNA encoding PGC‐1α4. Nanomicelle‐delivered Pgc‐1α4 mRNA enhances muscle damage resistance and mitochondrial activity in dystrophic muscles. This study demonstrates the potential of mRNA therapy for neuromuscular diseases like Duchenne muscular dystrophy and highlights
Xuan Du+7 more
wiley +1 more source
Variability of Terminology Used to Describe Unwanted Workplace Behaviors in Nursing: A Scoping Review. [PDF]
Lambert K, Francis K, Tori K.
europepmc +1 more source
Prevalence of co-occurring forms of intimate partner violence against women aged 15-49 and the role of education-related inequalities: analysis of Demographic and Health Surveys across 49 low-income and middle-income countries. [PDF]
Zhao S+19 more
europepmc +1 more source
Workplace violence, work characteristics, and seniority levels among nurses: a cross-sectional study. [PDF]
Yang HL+5 more
europepmc +1 more source
Understanding the influence of socioeconomic status on children physical disciplinary practices in Bangladeshi households. [PDF]
Ibrahim M, Patwary MH.
europepmc +1 more source
The effects of progressive muscle relaxation exercises on premenstrual syndrome symptoms and violence tendencies in women: a randomized controlled trial. [PDF]
Toğluk S, Gül S.
europepmc +1 more source