Results 91 to 100 of about 1,192,581 (339)

Modulating Purothionin Accumulation and Signal Peptide Cleavage Fine‐Tunes Wheat Flour Gluten Properties to Improve Cookie‐Making Quality

Advanced Science, EarlyView.
Dual genetic strategies for improving wheat processing quality by regulating purothionin accumulation to modulate gluten quantity and quality. The first strategy involves targeting signal peptide (SP) cleavage sites (e.g., through mutation) to indirectly reduce gluten content, thereby disrupting gluten network formation.
Yijie Liu, Siyuan Chang, Zhaoheng Zhang, Tianqi Kang, Mingde Liu, Yuan Zong, Fei Ni, Yinguang Bao, Ruijie Zhang, Xiaobang Zhang, Jinkun Du, Mingming Xin, Zhaorong Hu, Jie Liu, Zhongfu Ni, Qixin Sun, Yingyin Yao   +16 more
wiley   +1 more source

TRIM38 Suppresses Breast Cancer Progression via Modulating SQSTM1 Ubiquitination and Autophagic Flux

Advanced Science, EarlyView.
TRIM38, an E3 ubiquitin ligase, suppresses breast cancer progression by inhibiting proliferation, migration, and invasion. Downregulated in breast tumor, its loss correlates with poor prognosis. Mechanistically, TRIM38 mediates K63‐linked ubiquitination of SQSTM1/p62 at K420, disrupting SQSTM1‐LC3 interaction and blocking autophagic flux.
Shan Jiang, Lijuan Wang, Dianwen Han, Peng Su, Bing Chen, Wenjing Zhao, Tong Chen, Ning Zhang, Xiaolong Wang, Yiran Liang, Yaming Li, Chen Li, Xi Chen, Dan Luo, Qifeng Yang   +14 more
wiley   +1 more source

Global, regional, and national prevalence estimates of physical or sexual, or both, intimate partner violence against women in 2018

The Lancet, 2022
LynnMarie Sardinha, Mathieu Maheu-Giroux, H. Stöckl, S. Meyer, C. Garcia-Moreno   +4 more
semanticscholar   +1 more source

Gender, violence and Brexit [PDF]

, 2020
How will the UK exit from the EU affect gender-based violence against women? Four issues are addressed to answer this question. First, the importance of theorising the interconnections with a gender regime, including between gendered economic inequality ...
Walby, S.
core  

Commentary: Actions to end violence against women : a multi-sector approach [PDF]

, 2015
Many forms of violence affect women and girls, such as physical and sexual abuse, trafficking, female genital mutilation, early and forced marriage, murders in the name of honour or dowry, and sexual harassment and abuse by authority figures.
García-Moreno, Claudia, Temmerman, Marleen   +1 more
core   +4 more sources

The Gut Microbiota Regulates Motor Deficits via Butyrate in a Gnal+/− Mouse Model of DYT25 Dystonia

Advanced Science, EarlyView.
The present study provides compelling evidence for a modulatory role of the gut microbiota in the pathology of DYT25 dystonia, and butyrate supplementation alleviates the motor deficits of dystonia in Gnal+/− mice. Abstract Dystonia is the third most common movement disorder, following essential tremor and Parkinson's disease. The underlying mechanisms
Jingya Guo, Seong‐Gook Kang, Kunlun Huang, Tao Tong   +3 more
wiley   +1 more source

Honour-related violence (HRV) in Scotland: A cross- and multi-agency intervention involvement survey [PDF]

, 2007
This paper documents the results of a small-scale pilot study, which represents the first step towards further research in this overlooked area of violence against women and represents a first step towards responding to widespread calls for multi ...
Khan, R
core  

Proteogenomic Characterization Reveals Subtype‐Specific Therapeutic Potential for HER2‐Low Breast Cancer

Advanced Science, EarlyView.
Multiomic profiling of HER2‐low breast cancer identifies three proteomic subtypes with distinct therapeutic strategies: endocrine, antiangiogenic, and anti‐HER2 therapies. Genomic and lactate modification landscapes are detailed, providing insights for precise management.
Shouping Xu, Keda Yu, Lei Liu, Qin Wang, Xiaohui Wu, Yihai Chen, Guozheng Li, Xin Zhang, Bo Wei, Zitong Fu, Abiyasi Nanding, Zuxianglan Zhao, Lingbing Yang, Xingda Zhang, Jianyu Wang, Wantong Sun, Yi Hao, Zhongyi Cheng, Xiaojiang Cui, Hao Wu, Da Pang   +20 more
wiley   +1 more source

Mental health on two continua: mental wellbeing and common mental disorders in a community-based cross-sectional study with women in urban informal settlements in India

BMC Women's Health
Background We considered the suggestion that mental health is the product of two intersecting continua: psychological distress and mental wellbeing.
Suman Kanougiya, Nayreen Daruwalla, David Osrin   +2 more
doaj   +1 more source

Mediated representations of violence against women in the mainstream news in Australia

BMC Public Health, 2019
BackgroundHow the mainstream news media report violence against women is significant if levels of violence are to be reduced and ultimately eliminated.
G. Sutherland, P. Easteal, Kate Holland, C. Vaughan   +3 more
semanticscholar   +1 more source