This work identifies M1 macrophage‐mediated inflammation as a key driver of BMSC senescence and bone microstructural deterioration at the enthesis. A tissue‐adhesive hydrogel delivering senomorphic small extracellular vesicles suppresses this inflammatory‐senescent cascade and enhances BMSC resilience by inhibiting the cGAS‐STING‐NF‐κB pathway.
Lingzhi Kong +8 more
wiley +1 more source
Background Experiencing gender‐based violence (GBV) is common among refugees. Intersecting systems of oppression can increase the risk of GBV and of suffering detrimental consequences, while concurrently creating barriers to meaningful support.
Anna Pérez‐Aronsson +12 more
doaj +1 more source
Preventing and responding to gender-based violence in middle and low-income countries : a global review and analysis [PDF]
Worldwide, patterns of violence against women differ markedly from violence against men. For example, women are more likely than men to be sexually assaulted or killed by someone they know.
Bott, Sarah +2 more
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When I Was in My Home I Suffered a Lot: Mexican Women’s Descriptions of Abuse in Family of Origin [PDF]
In this descriptive study we employ episodic narrative interviews and narrative analysis to explore experiences of abuse and violence within the families of origin of Mexican women entering adulthood.
Belknap, Ruth, Cruz, Nancy
core +1 more source
Trained Memory of Uterine Macrophages Improves Subsequent Pregnancy Outcomes
This study identifies that pregnancy imprints a durable, pregnancy‐specific form of trained immune memory in uterine macrophages, marked by the emergence of LILRB3+/PIR‐B+ cells that expand across gestations, acquire a tolerogenic and metabolically rewired phenotype, and actively protect against inflammatory pregnancy loss in mice.
Jing Wang +8 more
wiley +1 more source
VICTIMS OF SEXUAL VIOLENCE ATTENDED IN A SPECIALIZED SERVICE
The aim was to investigate aspects of sexual violence and the victims’ adherence to outpatient follow-up. This transversal study involved retrospective data collection in a specialized service in the Brazilian state of Paraná.
Tatiane Herreira Trigueiro +5 more
doaj +1 more source
ANALISIS PUSPAGA BHAKTI PERTIWI SEBAGAI KOMUNIKASI PEMERINTAH DALAM UPAYA PENANGANAN KEKERASAN TERHADAP PEREMPUAN DAN ANAK DI KOTA BATU [PDF]
The Batu City Government through the P3AP2KB Service in its commitment through Batu City Regional Regulation Number 2 of 2013 concerning the Implementation of Protection for Women and Children Victims of Violence, where handling cases of violence against
Wulan, Sofia Retno
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It\u27s Not OK : New Zealand\u27s Efforts to Eliminate Violence Against Women [PDF]
Over the last decade, New Zealand has made significant efforts to address an acute social problem—violence against women. In New Zealand, it is estimated that one in three women has been a victim of domestic violence.
Contesse, Jorge, Fenrich, Jeanmarie
core +2 more sources
The Landscape and Regulation of Histone Crotonylation in Mammalian Gametes and Early Embryos
Histone crotonylation undergoes a genome‐wide transition from broad domains to canonical narrow peaks during minor zygotic genome activation (ZGA). This remodeling is required for proper major ZGA and blastocyst formation. Disruption of this transition by transcriptional inhibition, metabolic perturbation, or HDAC1 dysfunction impairs embryonic ...
Shenli Yuan +8 more
wiley +1 more source
Health and the primary prevention of violence against women [PDF]
This position paper focuses on the primary prevention of violence perpetrated by men against women. It develops a position on primary prevention (as distinct from secondary and tertiary interventions).
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