Results 181 to 190 of about 2,347 (246)

ExoSloNano: multimodal nanogold labels for identification of macromolecules in live cells and cryo-electron tomograms. [PDF]

Nat Methods
Young LN, Sherrard A, Zhou H, Shaikh F, Hutchings J, Riggi M, Narasimhan M, Flaherty WA, Bennett EJ, Rosen MK, Giraldez AJ, Villa E.   +11 more
europepmc   +1 more source

Endothelial PDGF Signaling Dysregulation Impairs Testicular Interstitial Homeostasis in Diabetes

Advanced Science, EarlyView.
Testicular endothelial cells (TECs) function as central signaling hubs that coordinate interstitial homeostasis. Diabetes disrupts TEC‐derived PDGF signaling, silences the JUND‐MCL1 survival program in Leydig cells, and impairs peritubular function, leading to fibrosis and testosterone insufficiency.
Wenxiu Zhang, Kai Hong, Yanling Tang, Lina Cui, Xiaojian Lu, Jianxing Cheng, Yangyi Fang, Qiaoling Jiang, Ziyan Zhuang, Songzhan Gao, Hui Jiang, Qiang Liu, Jingtao Guo, Zhe Zhang, Xiaoyan Wang   +14 more
wiley   +1 more source

Identification of M1 macrophage infiltration-related genes for immunotherapy in Her2-positive breast cancer based on bioinformatics analysis and machine learning. [PDF]

Sci Rep
Wang S, Wang X, Xia J, Mu Q.
europepmc   +1 more source

SAGE: Spatially Aware Gene Selection and Dual‐View Embedding Fusion for Domain Identification in Spatial Transcriptomics

Advanced Science, EarlyView.
SAGE is a unified framework for spatial domain identification in spatial transcriptomics that jointly models tissue architecture and gene programs. Topic‐driven gene selection (NMF plus classifier‐based scoring) highlights spatially informative genes, while dual‐view graph embedding fuses local expression and non‐local functional relations.
Yi He, Yunpei Xu, Liqing Ding, Hong‐Dong Li, Yaohang Li, Shaokai Wang   +5 more
wiley   +1 more source

Violins Unveiled: A Photogrammetric Framework Integrating Multiband and Spectroscopic Data for In-Depth Examination of Two Musical Instruments. [PDF]

Sensors (Basel)
Di Iorio F, Fiocco G, Angeloni R, Es Sebar L, Croci S, Cacciatori F, Malagodi M, Pozzi F, Grassini S.   +8 more
europepmc   +1 more source

Ultrafast Multilevel Switching and Synaptic Behavior in a Planar Quantum Topological Memristor

Advanced Science, EarlyView.
Dry‐transferred Bi2Te3 layers enable a planar quantum topological memristor framework. In‐plane topological surface states facilitate ultrafast & low‐power operations. Coexisting analog and digital modes support current‐controlled multilevel states. PQTM exhibits 105 s retention, 103 cycles endurance, and reproducibility across 24 devices.
Mamoon Ur Rashid, Usman Safder, Sobia Ali Khan, Anh‐Tuan Pham, Muhammad Sheeraz, Nguyen‐Hoang Dang, Duy Le Thanh, Zeeshan Tahir, Faisal Maqbool, Koo‐Hyun Chung, Sunglae Cho, Jungdae Kim, Yong Soo Kim   +12 more
wiley   +1 more source

A generalized platform for artificial intelligence-powered autonomous enzyme engineering. [PDF]

Nat Commun
Singh N, Lane S, Yu T, Lu J, Ramos A, Cui H, Zhao H.   +6 more
europepmc   +1 more source

Piece Dealing With Sorj Chalandon\u27s Award -Winning Novel About the Northern Ireland Conflict : an Irishman\u27s Diary [PDF]

, 2012
Maher, Eamon
core   +1 more source

BHLHE40 Orchestrates Effector Tissue‐Resident Memory CD8+ T Cells and Limits Long‐Term Survival of Kidney Graft

Advanced Science, EarlyView.
An effector subset of TRM, defined as CD49a+PD1hi CD8+ TRM, represents a BHLHE40‐orchestrated resident immune component that, rather than circulating cells, plays as a major contributor to allograft rejection. ABSTRACT Tissue‐resident memory T cells (TRM), which function against tumors, infections, and non‐self antigens in organ transplantation ...
Junbo Li, Bo Yang, Tianhui Pan, Xi Zhou, Zhibo Ma, Du Tang, Bowen Xie, Jing Liu, Zhishui Chen, Peixiang Lan   +9 more
wiley   +1 more source

Integrative transcriptomic and epigenomic analysis identifies BCL6B as a novel regulator of human pluripotent stem cell to endothelial differentiation. [PDF]

Protein Cell
Zhu Y, Liu J, Wang J, Ding S, Qiu H, Chen X, Guo J, Wang P, Zhang X, Zhang F, Huang R, Duan F, Wang L, Na J.   +13 more
europepmc   +1 more source