Results 221 to 230 of about 153,475 (260)

TNFR1 signaling connects inflammation to impaired fatty acid oxidation to drive intestinal stem cell aging. [PDF]

Nat Aging
Wang R, Tabrizian T, Wang D, English J, Ayer A, Gal M, Yang WL, Wu Z, Mao K, Novaj A, Zhang X, Basu I, Brodin NP, Koba W, Saxena D, Choi J, Augenlicht LH, Ericsson A, Gavathiotis E, Guha C, Huffman DM.   +20 more
europepmc   +1 more source

Glucocorticoid Receptor Signaling in Myeloid Cells Orchestrates Inflammation Resolution and Muscle Repair

Advanced Science, EarlyView.
Glucocorticoids (GC) are widely used to reduce inflammation. We show that the glucocorticoid receptor in myeloid cells regulates macrophage cell cycle and genome integrity during muscle regeneration. We demonstrate that dexamethasone administration during the early inflammatory phase delays muscle repair by increasing macrophage proliferation ...
Sirine Souali‐Crespo, Joe G. Rizk, Emilia Calvano, Rajesh Sahu, Emina Colovic, Imane Chabba, Valentine Gilbart, Erwan Grandgirard, Bastien Morlet, Qingshuang Cai, Daniel Metzger, Delphine Duteil   +11 more
wiley   +1 more source

Observational real-world analysis of dose-dependent effects of <i>Mitragyna speciosa (Korth.)</i> on focus and energy. [PDF]

Front Pharmacol
Shields CM, Kirk R, Chan M, Lehfeldt P, Brown PN.   +4 more
europepmc   +1 more source

An Unbiased Geometry‐Resolved Membrane Platform for Proteome‐Scale Discovery of Membrane Curvature Sensors

Advanced Science, EarlyView.
A novel geometry‐resolved membrane platform provides a seamlessly integrated pipeline for studying curvature‐sensing proteins. By linking shotgun proteomics with quantitative imaging, this approach enables both the unbiased discovery and rigorous validation of novel sensors across the entire curvature range—positive, negative, and zero.
Takumi Komikawa, Rikuto Kawakami, Kunanon Chattrairat, Tatsuya Niwa, Taiga Ajiri, Takao Yasui, Masayoshi Tanaka   +6 more
wiley   +1 more source

Clinical value of neutrophil-to-lymphocyte ratio and D-dimer in predicting the efficacy of minocycline for pediatric Mycoplasma pneumoniae pneumonia. [PDF]

Front Pediatr
Chen RF, Jiang X, Zhou X, Zhai Q, Wang J, Feng S.   +5 more
europepmc   +1 more source

Structural Divergence Between the Moltbook AI‐Agent Network and Human Social Networks

Advanced Science, EarlyView.
Analysis of the Moltbook AI‐agent network reveals a striking combination of familiar global scaling and distinct internal organization. Attention is highly concentrated, reciprocity is limited, connected triads are suppressed, and communities are strongly modular.
Wenpin Hou, Zhicheng Ji
wiley   +1 more source

Vancomycin Trough Concentrations and 24-Hour AUC Monitoring in Pediatric Patients.

JAMA Netw Open
Shiau J, Roy S, Sabourenkov P, Scheetz MH.   +3 more
europepmc   +1 more source

Multi-omics analysis of histidine metabolism reveals FRZB-CRYM-associated cellular crosstalk in heart failure. [PDF]

Front Cardiovasc Med
Xiao S, Mo C, Liu Q, Xu L.
europepmc   +1 more source

The GPX3‐VCAM1 Axis Gates Pro‐Fibrotic Tubule Cell Fate in Hyperuricemic Nephropathy

Advanced Science, EarlyView.
Hyperuricemia induces NLRP3 inflammasome signaling activation and downregulation of GPX3 in proximal tubular epithelial cells, leading to oxidative stress–driven VCAM1 upregulation, emergence of pro‐fibrotic proximal tubule cells, macrophage recruitment, and renal fibrosis.
Yunfei Qi, Qiang Zhao, Yue Lve, Yaming Yuan, Tingting Zhou, Yue Yuan, Dexi Wu, Yifan Tang, Yan Liu, Zhigang Li, Chunping Jiang, Qiurong Ding   +11 more
wiley   +1 more source

Safety and Cost Implications of General Ward versus Coronary Care Unit Admission After PCI for Stable STEMI: A Propensity-Matched Analysis. [PDF]

Int J Gen Med
Xu H, Ge L, Zhang Z, Deng X, Chen K, Jian L.   +5 more
europepmc   +1 more source