Results 161 to 170 of about 273,852 (324)

Sustainable Live Sound Monitoring and Classification System Enabled by a Triboelectric Nanogenerator and Machine Learning Techniques

open access: yesENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
A high‐performance Triboelectric Nanogenerator (TENG) acoustic sensor using polyimine/graphite polypropylene (PI/GP) was developed for real‐time, sustainable sound monitoring and classification. The self‐powered device delivers 25.67 μW output power, 92.7% accuracy with MobileNet V1, and powers a wireless transmission circuit, demonstrating dual ...
Majid Haji Bagheri   +8 more
wiley   +1 more source

Does spatialized audio enhance the creation of mental representations?

open access: yesFrontiers in Neuroscience
Navigating unfamiliar environments without vision is a considerable challenge for blind individuals, as it requires constructing accurate cognitive maps.
Shehzaib Shafique   +4 more
doaj   +1 more source

Mechanisms of SCN2A loss of function do not predict presence or phenotype of epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective SCN2A loss‐of‐function (LoF) variants are associated with epilepsy (onset age ≥ 3 months), intellectual disability (ID), and autism spectrum disorder (ASD). Despite numerous identified variants and the description of phenotypic subgroups, relationships between Nav1.2 channel dysfunction and clinical phenotypes remain unclear.
Marsha Tan   +23 more
wiley   +1 more source

One‐Stone‐Three‐Birds Biomimetic Oral Targeting Delivery Strategy for On‐Demand Controlled Drug Release and Intervertebral Disc Degeneration Therapy

open access: yesExploration, EarlyView.
ABSTRACT Intervertebral disc degeneration (IDD) is a multifactorial condition characterized by excessive inflammation, immune dysfunction, and metabolic disorders. Current therapeutic strategies primarily rely on local injection, a traumatic approach associated with risks of tissue damage and infection.
Yifan Ding   +8 more
wiley   +1 more source

The role of visual experience in haptic spatial perception: evidence from early blind, late blind, and sighted individuals

open access: yesBiology of Sex Differences
There is contradictory evidence on the effect that visual experience has on haptic abilities. Indeed, some studies have documented that a lack of vision (blindness) results in decreased haptic perception, whereas other studies report an enhanced haptic ...
Lara A. Coelho   +5 more
doaj   +1 more source

Isorhamnetin Alleviates Renal Fibrosis Induced by Renal Tubular Epithelial Cell Senescence Via Inhibition of the IL‐6/IL‐6R Signaling Pathway

open access: yesiMetaMed, EarlyView.
IL‐6 from RTECs upregulates TGF‐β in macrophages, promoting fibroblast transdifferentiation. Isorhamnetin inhibits this effect. ABSTRACT Chronic kidney disease (CKD) is a major global health issue. Kidney fibrosis is a key mechanism leading to end‐stage renal disease.
Weifei Liang   +8 more
wiley   +1 more source

Weizmannia coagulans XY2 Mitigates Copper Neurotoxicity via Gut–Brain Axis Modulation of Tryptophan Metabolism and Oxidative‐Inflammatory Crosstalk

open access: yesiMetaOmics, EarlyView.
Copper interferes with tryptophan metabolism and 5‐HT levels by modulating intestinal flora. Intestinal barrier breakdown and inflammatory response trigger nerve damage under copper exposure. W. coagulans XY2 alleviates copper‐induced neurotoxicity by targeting a multi‐dimensional “tryptophan metabolism‐antioxidant defense‐gut‐brain axis” network.
Yufang Gao, Xiaodong Zheng, Fujie Yan
wiley   +1 more source

Oleoylethanolamide regulates intestinal stem cell activity and villus size via PPARα signaling pathway

open access: yesiMetaOmics, EarlyView.
First use of a natural swine model with lipid metabolism to directly link lipid differences to a quantifiable intestinal villus height phenotype. Identified the phospholipid‐derived oleoylethanolamide, rather than canonical fatty acids, as the endogenous primary ligand that activates peroxisome proliferator‐activated receptors α (PPARα) to enlarge ...
Qianqian Wang   +9 more
wiley   +1 more source

卒中相关前庭症状

open access: yesZhongguo cuzhong zazhi, 2021
李佳树,王琰,李菁晶,李娜,方瑞乐,熊云云,刘改芬,赵性泉,鞠奕
doaj   +1 more source

Metabolic Signatures and Diagnostic Prediction Models for Coronary Artery Disease and Type 2 Diabetes Mellitus: Insights From an Exploratory Study

open access: yesiNew Medicine, EarlyView.
Metabolomic & lipidomic analysis reveals metabolic overlap between CAD & T2DM, highlighting 7 key metabolites as potential biomarkers. A predictive model based on these achieves high accuracy, potentially advancing precision medicine & metabolic insights.
Zhihua Wang   +9 more
wiley   +1 more source

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