Results 71 to 80 of about 790,626 (296)

Assessing water filtration and safe storage in households with young children of HIV-positive mothers: a randomized, controlled trial in Zambia. [PDF]

, 2012
BACKGROUND: Unsafe drinking water presents a particular threat to people living with HIV/AIDS (PLHIV) due to the increased risk of opportunistic infections, diarrhea-associated malabsorption of essential nutrients, and increased exposure to untreated ...
Clasen, Thomas, Peletz, R, Simunyama Martin, Sarenje Kelvin, Simunyama, Martin, Sarenje, Kelvin, Suzanne Filteau, Thomas Clasen, Rachel Peletz (132102), Filteau, S, Clasen Thomas, Paul Kelly, Martin Simunyama, Kathy Baisley (132119), Martin Simunyama (132107), Baisley, Kathy, Thomas Clasen (132131), Paul Kelly (95510), Simunyama, M, Peletz, Rachel, Clasen, T, Kathy Baisley, Filteau Suzanne, Filteau, Suzanne, Rachel Peletz, Kelvin Sarenje, Kelvin Sarenje (132113), Suzanne Filteau (132124), Peletz Rachel, Kelly Paul, Baisley Kathy, Baisley, K, Kelly, Paul, Sarenje, K, Kelly, P   +34 more
core   +1 more source

Distinct Cleavage Trajectories Mediated by DNA and RNA Substrate in Argonaute From Methanocaldococcus Fervens

Advanced Science, EarlyView.
This study characterizes MfAgo, an enzyme exhibiting highly efficient DNA‐guided DNA and RNA cleavage capability. Precise RNA cleavage strictly requires dimerization to stabilize the PIWI‐loop region, while its robust DNA cleavage functions in a dimerization‐independent manner.
Fuyong Huang, Taiyu Chen, Meng Fang, Qinmiao Duanmu, Kangle Mu, Yuqi Bi, Siwei Xu, Xin Tao, Jiening Wang, Shan Wu   +9 more
wiley   +1 more source

Epidemiology and Genetic Characterization of Classical Human Astrovirus Infection in Shanghai, 2015–2016

Frontiers in Microbiology, 2020
ObjectiveHuman astroviruses (HAstVs) are single-stranded RNA viruses of the Astroviridae family. Infection of classic HAstVs is one of the most common causes of acute viral gastroenteritis (infectious viral diarrhea).
Limeng Wu, Limeng Wu, Limeng Wu, Zheng Teng, Qingneng Lin, Jing Liu, Huanyu Wu, Xiaozhou Kuang, Xiaoqing Cui, Wei Wang, Xiaoxian Cui, Zheng-an Yuan, Xi Zhang, Youhua Xie   +13 more
doaj   +1 more source

A single nucleoside viral polymerase inhibitor against norovirus, rotavirus, and sapovirus-induced diarrhea

, 2018
A safe and highly efficient antiviral is needed for the prophylaxis and/or treatment of viral diarrhea. We here demonstrate the in vitro antiviral activity of four 2'-C-methyl nucleoside analogues against noro-, rota-, and sapoviruses.
Burrone O. R., Neyts J., Tarantino, Delia, Heylen, Elisabeth, Heylen E., Mastrangelo, Eloise, Papa G., Arnoldi, Francesca, Papa, Guido, Van Dycke J., Burrone, Oscar R., Rocha-Pereira J., Vandepoele J., Van Dycke, Jana, Vandepoele, Justine, Mastrangelo E., Tarantino D., Neyts, Johan, Rocha-Pereira, Joana, Arnoldi F., Tarantino D, Van Dycke J, Mastrangelo E, Arnoldi F, RochaPereira J, Papa G, Neyts J, Burrone OR, Heylen E, Vandepoele J   +29 more
core   +1 more source

Sex‐ and Time‐Resolved Physiological and Gut Ecosystem Responses to a Food‐Grade Microbiome‐Targeted Intervention in Collegiate Endurance Athletes

Advanced Science, EarlyView.
In collegiate endurance athletes, a 6‐week randomized CPYE intervention yielded time‐ and sex‐dependent shifts in field‐based cardiorespiratory, metabolic, and redox indices, accompanied by changes in gut multi‐omics profiles. An exploratory extension during intensified training generates hypotheses warranting future validation.
Meng Zhang, Le Ge, Kaiyang Liu, Yanrong Liu, Guolin Zhao, Lai‐Yu Kwok, Zheng Sun, Zhihong Sun, Wenyi Zhang   +8 more
wiley   +1 more source

Lyssavirus Nucleoprotein Induces GPAT4‐Mediated CYB5R1 Depalmitoylation to Suppress Ferroptosis and Promote Viral Replication

Advanced Science, EarlyView.
Lipid metabolism plays a vital role in viral infections. Here, we reveal that the lyssavirus N protein regulates GPAT4 to induce lipid droplet biogenesis, restricting CYB5R1 palmitoylation and reducing ferroptosis susceptibility to ultimately promote viral replication.
Jianqing Zhao, Chuan Liang, Pingping Chen, Meixin Sun, Zhen F. Fu, Ling Zhao, Ming Zhou   +6 more
wiley   +1 more source

DIARRHEA IN EARLY LIFE: PROGRESS IN DIAGNOSIS AND CONTROL OF DISEASE [PDF]

, 2010
Diarrheal diseases occurring in early life (< 3 years) are an heterogeneous group of abnormalities including gastrointestinal infections, food hypersensitivity and allergy, immune dysregulation, and primary abnormalities of the enterocyte.
Terrin, Gianluca
core   +1 more source

Kajian serologis Bovine Viral Diarrhea (BVD) pada sapi potong impor di daerah Jawa Barat

, 2013
Bovine viral diarrhea is a strategic infectious disease that should be concerned and priority controlled in Indonesia. BVD is a disease that can affect productivity and population growth of cattle.
Septiawaty, Mayang Suci
core  

Beyond Biomimetics: Pathology‐Informed Engineering Rescues Reconstituted HDL From Inflammatory Dysfunction for Sepsis Immunotherapy

Advanced Science, EarlyView.
A pathology‐informed engineering strategy rescues reconstituted HDL from inflammatory dysfunction in sepsis. By integrating a ceria nanozyme‐celastrol coordination complex, the platform preserves HDL structure and endotoxin handling, sustains hierarchical intracellular delivery, and enhances immunoregulation across pathological models, translating ...
Han Zhou, Lei Zhang, Xingyu Cai, Jiajia Su, Guangyu Dai, Xue Chen, Hanming Wang, Jia Hua, Jianping Liu, Chunmeng Sun, Xiancheng Chen, Erhao Wang, Wenli Zhang   +12 more
wiley   +1 more source

CLINICAL CHARACTERISTICS OF VIRAL GASTROENTERITIS OF MIXED ETIOLOGY IN YOUNG CHILDREN IN BAKU, AZERBAIJAN

Детские инфекции (Москва), 2018
The article presents the results of studying the etiological structure and clinical features of acute intestinal infections (AII) in young children in Baku, Azerbaijan.
Z. M. Kuliyeva, L. I. Rustamova, N. A. Azizova, M. M. Mukhtarov, M. N. Mamedova, N. N. Aliyeva   +5 more
doaj   +1 more source