Results 111 to 120 of about 6,506,858 (262)
Fast Facts:\ue2\u20ac\ua2 People with HIV infection are affected disproportionally by viral hepatitis.\ue2\u20ac\ua2 Nearly 75% of people with HIV who report a history of injection drug use also are infected with hepatitis C virus (HCV).\ue2\u20ac\ua2 ...
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Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Type-specific EV-D68 real-time RT-PCR assay for the detection of all extant enterovirus D68 strains
Journal of Clinical MicrobiologyWe developed a type-specific Enterovirus D68 (EV-D68) real-time RT-PCR (rRT-PCR) assay termed CDC2022, which targets sequences encoding conserved amino acid regions of all extant EV-D68 strains. We targeted three motifs conserved among all strains in the
Terry Fei Fan Ng +6 more
doaj +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Progress toward viral hepatitis elimination in the United States, 2017 : national progress report with data through 2015 [PDF]
The Centers for Disease Control and Prevention (CDC) strives to prevent viral hepatitis infections and to eliminate disease and mortality caused by viral hepatitis.
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Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
The ABCs of viral hepatitis [PDF]
Millions of Americans have viral hepatitis and an estimated 72,000 become infected each year. When a person first gets viral hepatitis, he or she can develop a very mild illness with few or no symptoms or get a more serious illness lasting months ...
core +2 more sources
Animal BiotechnologyMesenchymal stem cells (MSCs) can self-renew and differentiate into several lineages and can be isolated from different tissues such as bone marrow, adipose tissue, umbilical cord blood, and muscle.
Na-Yeon Gu +6 more
doaj +1 more source
Viral hepatitis surveillance United States, 2013 [PDF]
As part of the Centers for Disease Control and Prevention\ue2\u20ac\u2122s (CDC) National Notifiable Diseases Surveillance System (NNDSS), viral hepatitis case-reports are received electronically from state and territorial health departments via CDC\ue2 ...
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Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
FEBS Open Bio, EarlyView.We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source