Results 251 to 260 of about 1,330,033 (311)
Advanced Science, EarlyView.Fibronectin 1 (FN1)‐expressing subicular subpopulations encode novel object preference and selectively govern retrieval of novel object recognition (NOR) via affecting excitability of entorhinal‐projecting circuit through large conductance Ca2+‐activated potassium (BK) channel. ABSTRACT Novel object recognition (NOR), referring to the cognitive ability
Fan Fei +15 more
wiley +1 more source
Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain
Advanced Science, EarlyView.This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao +7 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT Brown and beige adipocytes dissipate energy as heat, yet effective strategies to enhance their mitochondrial efficiency remain limited. Here, we identify Agnuside (AGN) as a selective stabilizer of the complex I assembly factor NDUFAF6. AGN directly binds cytosolic NDUFAF6, suppresses its ubiquitination, prolongs its half‐life, and facilitates
Qingwen Zhao +7 more
wiley +1 more source
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2020
Viruses cause many important plant diseases and are responsible for yield and quality losses in crops in all parts of the world. No curative methods are available for infected plants and the main control strategies are cultural practices including prophylactic measures to prevent virus arrival, installation and spread into the crop or use genetic ...
Moriones, Enrique, Verdin, Eric
openaire +1 more source
Viruses cause many important plant diseases and are responsible for yield and quality losses in crops in all parts of the world. No curative methods are available for infected plants and the main control strategies are cultural practices including prophylactic measures to prevent virus arrival, installation and spread into the crop or use genetic ...
Moriones, Enrique, Verdin, Eric
openaire +1 more source
2022
This chapter focuses on key virus families that affect wild and cultured insect species and describes current knowledge on the molecular and ecological aspects of these viruses. Insects can be infected by a variety of viruses each with distinct properties and pathologies.
Ros, V.I.D. +5 more
openaire +2 more sources
This chapter focuses on key virus families that affect wild and cultured insect species and describes current knowledge on the molecular and ecological aspects of these viruses. Insects can be infected by a variety of viruses each with distinct properties and pathologies.
Ros, V.I.D. +5 more
openaire +2 more sources
Hematology, 2000
As part of the international outreach of the American Society of Hematology, this review addresses some aspects of the genetics, biology, epidemiology, and clinical relevance of viruses that cause a variety of hematopoietic disorders in human populations.
Genoveffa, Franchini +2 more
openaire +2 more sources
As part of the international outreach of the American Society of Hematology, this review addresses some aspects of the genetics, biology, epidemiology, and clinical relevance of viruses that cause a variety of hematopoietic disorders in human populations.
Genoveffa, Franchini +2 more
openaire +2 more sources