Results 151 to 160 of about 965,577 (264)

Enhancing Small Molecule Sensing With Aptameric Functionalized Nano Devices

Advanced Materials Technologies, EarlyView.
Unveiling an ultra‐sensitive, non‐invasive neurotransmitter sensor. For the first time, a nanoscale sensor for detecting an important neurotransmitter was demonstrated using micro‐electromechanical systems (MEMS) technology. Our approach utilized field‐effect transistor (FET)‐based readout to enable pico‐molar detection of biomarkers in sweat.
Thi Thanh Ha Nguyen, Cong Minh Nguyen, Quang Thang Trinh, Minh Anh Huynh, Khanh Vinh Ho, Dang Co Pham, Dzung Dao, Sven Ingebrandt, Sina Jamali, Xuan Thang Vu, Nam‐Trung Nguyen, Tuan‐Khoa Nguyen   +11 more
wiley   +1 more source

Different SARS-CoV-2 Subvariants and Coagulation Markers Trend: A Retrospective Multicentric Study From Iranian Network for Research in Viral Diseases (INRVD). [PDF]

Health Sci Rep
Razavi A, Koltapeh MP, Nazari T, Morvaridi A, Banivaheb B, Saeb S, Moulaeian M, Zakaryaei A, Sabzalian A, Raei M, Razavi B, Motlaghzadeh S, Hosseini SS, Karami H, Ghafari P, Aboofazeli A, Nastarvand S, Sarabi NKN, Avakian A, Ebadinejad S, Keyhani T, Danafar P, Rahimlou R, Heidarian S, Mondeali M, Nafe-Monfared F, Jafarpour M, Samiee M, Birang F, Mirzazadeh A, Abadi SAF, Barkhordari K, Siavoshi S, Biklari M, Khodabakhsh M, Javadi A, Mirzaee S, Didgar F, Etebari M, Soltanmohamad S, Shahbaz B, Kord E, Shahri SMH, Ebrahimzade M, Moghaddam AA, Sanavi FS, Moattari A, Edalat F, Sheijani MF, Moghadami M, Yaghubi T, Mojtahedi A, Heidarzadeh A, Naghipour M, Luyeh MS, Nazemi P, Alipasandi K, Albaji M, Afzali M, Shokouhi N, Ezani A, Najari HR, Hosseini M, Ghobadi A, Momeni A, Fattahi SZ, Mohsenzadeh M, Jafari M, Azizi A, Pouryousef S, Tabarraei A, Moradi A, Azimi S, Yahyapour Y, Bayani M, Poortahmasebi V, Varshochi M, Ziaee M, Ghafari S, Javanmard D, Soleimani A, Mozhgani SH, Mokhames Z, Akhoundimeybodi Z, Astani A, Abdollahi A, Hadadi A, Salehi MR, Hajiabdolbaghi M, Raeeskarami SR, Kafan S, Montazeri M, Pazoki M, Riahi T, Talebi-Taher M, Ataei-Pirkooh A, Bokharaei-Salim F, Faiz SHR, Kalantari S, Yasin Z, Jazayeri SM.   +100 more
europepmc   +1 more source

Microneedles Mediated Delivery of Nanodiamonds for Quantum Sensing of Free Radicals in Skin Tissue

Advanced Materials Technologies, EarlyView.
Fluorescent nanodiamonds are nanoscale sensors capable of monitoring cellular stress responses. However, to function effectively, they must be delivered into cells or tissues. Here, we demonstrate their application in the skin by developing a dissolvable microneedle platform that dissolves after skin insertion, enabling the delivery of nanodiamonds ...
Siyu Fan, Maria Carmona Lobita, Thea Vedelaar, Yue Zhang, Claudia Reyes‐San‐Martin, Tomás Bauleth‐Ramos, Gésinda Geertsema‐Doornbusch, Han Gao, Mohammad‐Ali Shahbazi, Hélder A. Santos, Romana Schirhagl   +10 more
wiley   +1 more source

Advances in CRISPR-Cas12a/13a-Based Nucleic Acid Detection for Porcine Viral Diseases: A Comprehensive Review. [PDF]

Vet Sci
Zhang X, Zhao X, Song Y, Luo Y, Yao L, Wu Q, Ye T, Liang W, Zhang X, Liang Y, Liang B, Zhang J, Li X.   +12 more
europepmc   +1 more source

Piezo2 Mediates a Vicious Cycle of “Mechanical Homeostasis Imbalance—Inflammation” in Sensory Nerves and the Cartilage Endplate

Advanced Science, EarlyView.
In a lumbar spine instability model, dorsal root ganglion cells mediate the perception of relevant mechanical stresses through Piezo2 and subsequently release CGRP. CGRP activates the NF‐κB signaling pathway in cartilage endplate cells through the receptor RAMP1.
Hanpeng Xu, Wen Geng, Zhi Du, Yifan Du, Di Wu, Bide Tong, Huaizhen Liang, Xingyu Zhou, Zixuan Ou, Junyu Wei, Kun Wang, Yu Song, Wenbin Hua, Yan Xu, Wencan Ke, Bingjin Wang, Cao Yang   +16 more
wiley   +1 more source

PROTACs in the treatment of viral diseases. [PDF]

Future Med Chem
Bhole RP, Kute P, Gurav SS.
europepmc   +1 more source

QBP1 Peptide as a Potential Anti‐Amyloidogenic Therapy for Type 2 Diabetes: An In Vitro Study

Advanced Science, EarlyView.
The anti‐amyloidogenic peptide QBP1 effectively halts human islet amyloid polypeptide (hIAPP) aggregation, preventing the formation of toxic β‐structured intermediates. Through a combination of biophysical assays, molecular dynamics, and cell‐based studies, QBP1 is shown to preserve β‐cell viability and metabolic homeostasis, positioning it as a ...
María M. Tejero‐Ojeda, Ada Bernaus Vives, Michał Wojciechowski, Dinh Quoc Huy Pham, Mateusz Chwastyk, Mario Vallejo, Anna Novials, Douglas V. Laurents, Mariano Carrión‐Vázquez   +8 more
wiley   +1 more source

mRNA Vaccine Development in the Fight Against Zoonotic Viral Diseases. [PDF]

Viruses
Tan BEK, Tham SK, Poh CL.
europepmc   +1 more source

Malectin Alleviates Endoplasmic Reticulum Stress in Gestational Diabetes Mellitus via Glycoprotein Quality Control Mechanisms

Advanced Science, EarlyView.
Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu, Yumeng Zhang, Ye Wang, Xiaoyu Zhu, Ailin Yuan, Weijing Yin, Huangmin Yu, Xuemin Pang, Yufeng He, Yuchen Wang, Tong Wang, Yong Li, Yunlong Si   +12 more
wiley   +1 more source

Viral Diseases Explorer: a webtool to identify viral disease information derived from multiple LLMs. [PDF]

Bioinformatics
Rojas Labra O, Martinez-Garcia CM, Santoyo-Rivera N, Montiel-Garcia D, Reddy VS.   +4 more
europepmc   +1 more source