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Exploiting viral genetic diversity to uncover sharka dispersal at regional and local scales
, 2016 Sylvie Dallot +5 more
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Unity and diversity among viral kinases
Gene, 2020Viral kinases are known to undergo autophosphorylation and also phosphorylate viral and host substrates. Viral kinases have been implicated in various diseases and are also known to acquire host kinases for mimicking cellular functions and exhibit virulence.
Chintalapati Janaki +3 more
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Viral diversity in acute infection
Nature Reviews Microbiology, 2020This study reported the diversity of CMV, HIV-1 and RSV viral populations during acute infection from clinical samples.
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Science, 2009
Detailed analyses of population demographics and viral diversity should help predict the impact of childhood vaccination for endemic viruses such as rotavirus.
Graham F. Medley, D. James Nokes
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Detailed analyses of population demographics and viral diversity should help predict the impact of childhood vaccination for endemic viruses such as rotavirus.
Graham F. Medley, D. James Nokes
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HIV-1 superinfection and viral diversity
AIDS, 2004Sequential acquisition of viral variants, or HIV-1 superinfection, has been proposed to explain the high fractions of recombinant viruses observed in some geographical regions, but only a few cases of superinfection in humans have been reported. Animal models suggest that susceptibility to superinfection may be restricted to a short period of time ...
Kimber L, Gross +2 more
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Within-Host Viral Diversity: A Window into Viral Evolution
Annual Review of Virology, 2020The evolutionary dynamics of a virus can differ within hosts and across populations. Studies of within-host evolution provide an important link between experimental studies of virus evolution and large-scale phylodynamic analyses. They can determine the extent to which global processes are recapitulated on local scales and how accurately experimental ...
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Structural and functional diversity of viral IRESes
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2009Some 20 years ago, the study of picornaviral RNA translation led to the characterization of an alternative mechanism of initiation by direct ribosome binding to the 5' UTR. By using a bicistronic vector, it was shown that the 5' UTR of the poliovirus (PV) or the Encephalomyelitis virus (EMCV) had the ability to bind the 43S preinitiation complex in a 5'
Laurent, Balvay +4 more
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Viral glycoprotein heterogeneity-enhancement of functional diversity
Glycoconjugate Journal, 1992Variations in the amino acid sequence of RNA virus envelope glycoproteins can cause changes in their antigenicity and can alter the host-cell tropism of the virus and the degree of virulence which it exhibits. Such changes may alter the course and outcome of viral diseases, either directly because of changes in the biological properties of the ...
I T, Schulze, I D, Manger
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Diversity Analysis in Viral Metagenomes
2018Viruses are the most abundant and diverse biological entity in the earth. Nowadays, there are several viral metagenomes from different ecological niches which have been used to characterize new viral particles and to determine their diversity. However, viral metagenomic data have the disadvantage to be high-dimensional compositional and sparse.
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