Results 1 to 10 of about 40,559 (249)
Computational approaches in viral ecology [PDF]
Computational and Structural Biotechnology Journal, 2020 Dynamic virus-host interactions play a critical role in regulating microbial community structure and function. Yet for decades prior to the genomics era, viruses were largely overlooked in microbial ecology research, as only low-throughput culture-based ...
Varada Khot +2 more
doaj +6 more sources
The Ecology of Viral Emergence
Annual Review of Virology, 2022 The coronavirus disease 2019 (COVID-19) pandemic has had a profound impact on human health, economic well-being, and societal function. It is essential that we use this generational experience to better understand the processes that underpin the emergence of COVID-19 and other zoonotic diseases.
Edward C Holmes
exaly +3 more sources
Extension of the viral ecology in humans using viral profile hidden Markov models. [PDF]
PLoS One, 2018 When human samples are sequenced, many assembled contigs are "unknown", as conventional alignments find no similarity to known sequences. Hidden Markov models (HMM) exploit the positions of specific nucleotides in protein-encoding codons in various microbes. The algorithm HMMER3 implements HMM using a reference set of sequences encoding viral proteins,
Bzhalava Z, Hultin E, Dillner J.
europepmc +5 more sources
Viral Recombination: Ecology, Evolution, and Pathogenesis [PDF]
Viruses, 2018 Recombination between and within virus genomes is being increasingly recognized as a majordriver of virus evolution.
Kenneth M. Stedman
doaj +3 more sources
Altered oral viral ecology in association with periodontal disease. [PDF]
mBio, 2014 ABSTRACTThe human oral cavity is home to a large and diverse community of viruses that have yet to be characterized in patients with periodontal disease. We recruited and sampled saliva and oral biofilm from a cohort of humans either periodontally healthy or with mild or significant periodontal disease to discern whether there are differences in viral ...
Ly M +6 more
europepmc +7 more sources
Ecosystem health shapes viral ecology in peatland soils. [PDF]
Nat MicrobiolAbstract Peatlands hold up to one-third of Earth’s soil carbon but are increasingly turning from being carbon sinks to becoming carbon sources due to human impacts. Restoration efforts aim to reverse this trend, but viral influences on peatland recovery remain unclear, despite viruses being potent regulators of microbiomes and ...
Kosmopoulos JC +3 more
europepmc +5 more sources
454-Pyrosequencing: A Molecular Battiscope for Freshwater Viral Ecology [PDF]
Genes, 2010 Viruses, the most abundant biological entities on the planet, are capable of infecting organisms from all three branches of life, although the majority infect bacteria where the greatest degree of cellular diversity lies. However, the characterization and assessment of viral diversity in natural environments is only beginning to become a possibility ...
James Mcdonald +2 more
exaly +4 more sources
Viromics approaches for the study of viral diversity and ecology in microbiomes [PDF]
Nature Reviews GeneticsViruses are found across all ecosystems and infect every type of organism on Earth. Traditional culture-based methods have proven insufficient to explore this viral diversity at scale, driving the development of viromics, the sequence-based analysis of uncultivated viruses.
Simon Roux +2 more
exaly +3 more sources
Viral ecology comes of age [PDF]
Environmental Microbiology Reports, 2017 Steven W Wilhelm +2 more
exaly +3 more sources
Host-linked soil viral ecology along a permafrost thaw gradient [PDF]
Nature Microbiology, 2018 Gareth Trubl +2 more
exaly +2 more sources