Results 181 to 190 of about 238,327 (306)

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

Chaperoning viral protein evolution

, 2018
Thesis: Ph. D. in Biological Chemistry, Massachusetts Institute of Technology, Department of Chemistry, 2018.Cataloged from PDF version of thesis. Vita.Includes bibliographical references.Preventing viral pandemics and developing effective antiviral ...
Phillips, Angela Marie, Ph. D. Massachusetts Institute of Technology
core  

Intrahost viral evolution of SARS-CoV-2 infections in rheumatic versus hematological patients with severe iatrogenic immunosuppression. [PDF]

Front Med (Lausanne)
Karofylakis E, Loupis T, Blizou A, Ntalaouti E, Stergioti EM, Vatsellas G, Tsiodras S, Antoniadou A, Banos A, Thomas K.   +9 more
europepmc   +1 more source

CAR T‐Cell Therapy in Neurology: A Scoping Review of Neuro‐Oncology, Autoimmune Diseases & Neurotoxicity

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi, Mohammed Dibas, Patricia Tai, Ala Dibas, Osama Souied, Suhair Al‐Ghabeesh   +5 more
wiley   +1 more source

The mutational landscape of SARS-CoV-2 provides new insight into viral evolution and fitness. [PDF]

Nat Commun
Symons J, Chung C, Verheijen BM, Shemtov SJ, de Jong D, Amatngalim G, Nijhuis M, Vermulst M, Gout JF.   +8 more
europepmc   +2 more sources

A combination of broadly neutralizing antibodies prevents in vitro SHIV162p3 cell-free transmission more efficiently than cell to cell transmission

Journal of Virus Eradication, 2016
K. Suphaphiphat, M. Tolazzi, G. Scarlatti, R. Legrand, M. Cavarelli   +4 more
doaj   +1 more source

Chronic infections can generate SARS-CoV-2-like bursts of viral evolution without epistasis. [PDF]

Virus Evol
Rodríguez-Horta E, Strahan J, Dinner AR, Barton JP.   +3 more
europepmc   +1 more source

Viral Evolution Shaped by Host Proteostasis Networks. [PDF]

Annu Rev Virol, 2023
Yoon J, Patrick JE, Ogbunugafor CB, Shoulders MD.   +3 more
europepmc   +1 more source

Neurovascular Contacts in the Pathophysiology of Neuralgic Amyotrophy: An Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuralgic amyotrophy (NA) is a prevalent, monophasic, multifocal immune‐mediated neuropathy. A distinctive characteristic of the disease is the occurrence of nerve or fascicle constrictions and torsions (NA‐associated focal nerve lesions, NAFL). The pathophysiology underlying this phenomenon remains to be fully elucidated.
Johannes Fabian Holle, Andreas Leha, Volker Limmroth, Wolfram Windisch, Maximilian Zimmermann   +4 more
wiley   +1 more source

Affinity maturation and light-chain-mediated paratope diversification anticipates viral evolution. [PDF]

Cell Rep
Dingus J, Yoo DK, Kumar S, Wang Y, Kibria MG, Saghaei S, Allahyari Z, Chen JW, Caputo NM, Hwang J, Chen B, Wesemann DR.   +11 more
europepmc   +1 more source