Results 221 to 230 of about 221,738 (262)

Investigating the Genetic Diversity of Hepatitis Delta Virus in Hepatocellular Carcinoma (HCC): Impact on Viral Evolution and Oncogenesis in HCC. [PDF]

Viruses
Juang HH, Hsu CW, Chang KS, Iang SB, Lin YH, Chao M.   +5 more
europepmc   +1 more source

Resolving Heterogeneity of Targeted Lipid Nanoparticles Through Solution‐Based Biophysical Analyses

Advanced Materials, EarlyView.
AF4‐UV‐DLS‐MALS‐SAXS resolves previously inaccessible targeted lipid nanoparticle (tLNP) subpopulations that differ in size, shape, and composition. Correlation of subpopulation‐resolved biophysical properties with in vivo RNA delivery reveals that targeted placental transfection is associated with distinct tLNP subpopulations rather than ensemble ...
Hannah C. Geisler, Hannah C. Safford, Ajay S. Thatte, Marshall S. Padilla, Elisa Battistini, Hannah M. Yamagata, Violet M. Ullman, Alex Chan, Benjamin E. Nachod, Anushka Agrawal, Maxwell B. Watkins, Jesse B. Hopkins, Andrew Tsourkas, Kushol Gupta, Michael J. Mitchell   +14 more
wiley   +1 more source

Boolean Logic‐Based Control Over Recombinant Protein Biomaterial Degradability and Therapeutic Delivery

Advanced Materials, EarlyView.
Fully recombinant protein‐based biomaterials execute complex Boolean logic for user‐programmable material degradation and concomitant therapeutic cargo release. Biologics, such as growth factors, can be incorporated within the crosslinkers as “drugamers”, while encapsulated cells can be released according to nested YES/OR/AND‐type logical operations ...
Murial L. Ross, Ryan Gharios, Shivani Kottantharayil, Cole A. DeForest   +3 more
wiley   +1 more source

Conserved untranslated regions of multipartite viruses: Natural markers of novel viral genomic components and tags of viral evolution. [PDF]

Virus Evol
Zhang S, Yang C, Qiu Y, Liao R, Xuan Z, Ren F, Dong Y, Xie X, Han Y, Wu D, Ramos-González PL, Freitas-Astúa J, Yang H, Zhou C, Cao M.   +14 more
europepmc   +1 more source

[NO in viral mutation and evolution].

Uirusu, 2000
openaire   +1 more source

Evolution of viral genomes and their clouds of sequence

Proceedings of the National Academy of Sciences
openaire   +2 more sources

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Evolution of a viral nucleocapid

Nature Reviews Microbiology, 2021
This study reports the evolution of a bacterial enzyme that does not have an inherent RNA-binding activity into a virus-like nucleocapsid protein that efficiently packages and encapsidates copies of its own mRNA.
York Ashley
exaly   +3 more sources

Networks and viral evolution

Journal of Molecular Evolution, 1997
In studying population data, it is common to have many equally possible parsimonious trees. This has caused representational problems, all of which have been addressed by using various kinds of consensus trees. Recognizing that the incubus may in fact be the constraint of having to have a tree representation, several authors have investigated networks ...
openaire   +2 more sources

Immuno-epidemiology and the predictability of viral evolution

Science, 2022
Understanding viral evolution depends on a synthesis of evolutionary biology and immuno ...
Chadi M, Saad-Roy, C Jessica E, Metcalf, Bryan T, Grenfell   +2 more
openaire   +2 more sources

Within-Host Viral Diversity: A Window into Viral Evolution

Annual Review of Virology, 2020
The evolutionary dynamics of a virus can differ within hosts and across populations. Studies of within-host evolution provide an important link between experimental studies of virus evolution and large-scale phylodynamic analyses. They can determine the extent to which global processes are recapitulated on local scales and how accurately experimental ...
openaire   +2 more sources