Results 281 to 290 of about 4,157,307 (334)

Surface‐Capped Protein Nanoparticles for Nonviral Gene Delivery

Advanced Materials, EarlyView.
ABSTRACT Developing simple, safe, and efficient nonviral delivery systems remains a significant challenge in bioengineering. Nanoparticles offer promising gene delivery capabilities with reduced toxicity; however, long‐standing challenges related to effective plasmid encapsulation and delivery exist.
Fjorela Xhyliu, Yao Yao, Yeongun Ko, Grant Grasman, Jeffery E. Raymond, Albert Chang, Yuxuan Deng, Grant Dominic, Michael Triebwasser, Joerg Lahann   +9 more
wiley   +1 more source

Rethinking Extracellular Vesicle Signaling

Advanced Materials, EarlyView.
Extracellular vesicles enable cell communication beyond intracellular cargo delivery. This perspective highlights two plausible surface‐based signaling modes: “bind‐and‐stay” and “bind‐and‐leave.” Transient binding to multiple cells challenges the one‐vesicle‐one‐cell model.
Wojciech Chrzanowski, Joy Wolfram
wiley   +1 more source

Genomic Expedition: Deciphering Human Adenovirus Strains from the 2023 Outbreak in West Bengal, India: Insights into Viral Evolution and Molecular Epidemiology. [PDF]

Viruses
Chatterjee A, Bhattacharjee U, Gupta R, Debnath A, Majumdar A, Saha R, Chawla-Sarkar M, Chakrabarti AK, Dutta S.   +8 more
europepmc   +1 more source

[Viral hepatitis; evolutive types].

Revista chilena de pediatria, 2003
openaire   +1 more source

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Viral evolution: beyond drift and shift.

Current Opinion in Microbiology, 2015
Technological advances have allowed aspects of viral evolution to be explored at unprecedented scales. As a consequence, new quantitative approaches are needed to investigate features of viral evolution that fall outside traditional areas of study, such as antigenic evolution.
B. Greenbaum, E. Ghedin
semanticscholar   +3 more sources

Cooperation: another mechanism of viral evolution.

Trends in Microbiology, 2013
RNA viruses evolve rapidly under selection pressure as a result of the high error rates of viral RNA polymerase. 'Cooperation' between wild type and variant measles virus (MV) genomes through the heterooligomer formation of a viral protein has recently been shown to act as a mechanism of viral evolution.
Yuta Shirogane, Shumpei Watanabe, Y. Yanagi   +2 more
semanticscholar   +3 more sources

Evolution of a viral nucleocapid

Nature Reviews Microbiology, 2021
This study reports the evolution of a bacterial enzyme that does not have an inherent RNA-binding activity into a virus-like nucleocapsid protein that efficiently packages and encapsidates copies of its own mRNA.
openaire   +2 more sources

Intrahost viral evolution during chronic sapovirus infections.

Journal of Clinical Virology, 2019
BACKGROUND Sapovirus is a common cause of self-limiting diarrhea. In immunocompromised individuals chronic infections occur, but are incompletely investigated.
C. Pietsch, U. Liebert
semanticscholar   +1 more source

Immune response and within-host viral evolution: Immune response can accelerate evolution.

Journal of Theoretical Biology, 2018
The objectives of this paper are to explore the impact of immune response on within-host viral evolution towards higher Darwinian fitness and, in particular, to verify a hypothesis that immune response, which is insufficient to annihilate a viral ...
A. Korobeinikov
semanticscholar   +1 more source