Results 291 to 300 of about 4,157,307 (334)

Networks and viral evolution

Journal of Molecular Evolution, 1997
In studying population data, it is common to have many equally possible parsimonious trees. This has caused representational problems, all of which have been addressed by using various kinds of consensus trees. Recognizing that the incubus may in fact be the constraint of having to have a tree representation, several authors have investigated networks ...
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Evolution, Viral

2009
Recent progress in comparative genomic and structural biology of microbial viruses, together with the discovery of unusual viruses in archaea and a giant virus in eukarya, has rejuvenated discussion on the origin of viruses. Many scientists now believe that viruses predated the Last Universal Common Ancestor (LUCA).
openaire   +1 more source

Viral Persistence: Evolution of Viral Populations

1980
There is an extensive literature dealing with persistent infections established by a wide variety of animal viruses. Several mechanisms have been suggested that may be involved in the establishment and maintenance of persistent infection by a normally virulent, cytolytic virus.
Julius S. Youngner, Olivia T. Preble
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Implications of mixed viral infections on plant disease ecology and evolution.

Advances in Virus Research, 2020
Mixed viral infections occur more commonly than would be expected by chance in nature. Virus-virus interactions may affect viral traits and leave a genetic signature in the population, and thus influence the prevalence and emergence of viral diseases ...
C. Alcaide, M. P. Rabadán, Manuel G. Moreno-Pérez, P. Gómez   +3 more
semanticscholar   +1 more source

SARS-CoV-2 viral clearance and evolution varies by type and severity of immunodeficiency

Science Translational Medicine
Despite vaccination and antiviral therapies, immunocompromised individuals are at risk for prolonged severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, but the immune defects that predispose an individual to persistent coronavirus ...
Yijia Li, M. Choudhary, J. Regan, J. Boucau, Anusha Nathan, Tessa Speidel, M. Y. Liew, Gregory E. Edelstein, Yumeko Kawano, R. Uddin, Rinki Deo, C. Marino, Matthew A. Getz, Z. Reynolds, Mamadou Barry, R. Gilbert, Dessie Tien, S. Sagar, T. Vyas, J. P. Flynn, Sarah P. Hammond, L. Novack, B. Choi, M. Cernadas, Z. Wallace, Jeffrey A. Sparks, J. Vyas, Michael S. Seaman, Gaurav D. Gaiha, M. Siedner, A. Barczak, Jacob E. Lemieux, Jonathan Z. Li   +32 more
semanticscholar   +1 more source

Genetic Diversity and Evolution of Viral Populations

Reference Module in Life Sciences, 2019
Population genetic diversity plays a prominent role in viral evolution, pathogenesis, immune escape, and drug resistance. Different mechanisms are responsible for creating and maintaining genetic diversity in viruses, including error-prone replication ...

semanticscholar   +1 more source

Evolution of the Large Nucleocytoplasmic DNA Viruses of Eukaryotes and Convergent Origins of Viral Gigantism.

Advances in Virus Research, 2019
The Nucleocytoplasmic Large DNA Viruses (NCLDV) of eukaryotes (proposed order "Megavirales") comprise an expansive group of eukaryotic viruses that consists of the families Poxviridae, Asfarviridae, Iridoviridae, Ascoviridae, Phycodnaviridae ...
E. Koonin, N. Yutin
semanticscholar   +1 more source

Evolution of viral DNA-dependent RNA polymerases

Virus Genes, 1995
The DNA-dependent RNA polymerase (DdRP or RNAP) is an essential enzyme of transcription of replicating systems of prokaryotic and eukaryotic organisms as well as cytoplasmic DNA viruses. DdRPs are complex multisubunit enzymes consisting of 8-14 subunits, including two large subunits and several smaller polypeptides (small subunits). An extensive search
K C, Sonntag, G, Darai
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Beyond Omicron: what’s next for COVID’s viral evolution

Nature, 2021
E. Callaway
semanticscholar   +1 more source

Evolution of viral pandemics

Medical Journal Armed Forces India, 2022
openaire   +2 more sources