Results 151 to 160 of about 463,872 (305)

Human Immunodeficiency Virus (HIV) viral load suppression status and associated factors among pregnant women receiving Highly Active Antiretroviral Therapy (HAART) in Ethiopia

open access: yesVirology Journal
Background Mothers with an undetectable viral load pose no risk of transmitting the Human Immunodeficiency Virus (HIV) to their fetuses. However, there is limited information on the HIV viral suppression status (≤ 1000 RNA copies/mL) among pregnant ...
Getnet Hailu   +11 more
doaj   +1 more source

Membrane Fusion‐Inspired Nanomaterials: Emerging Strategies for Infectious Disease and Cancer Diagnostics

open access: yesAdvanced Healthcare Materials, EarlyView.
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee   +9 more
wiley   +1 more source

Evaluating the accuracy of HIV-1 viral load testing using near point of care Xpert HIV-1 system at Solwezi general hospital, Zambia

open access: yesBMC Research Notes
Objective HIV-1 Viral Load Testing plays a crucial role in the management of HIV/AIDS patients by quantifying the presence of HIV-1 RNA in the blood, which directly relates to viral replication and disease progression.
Keembe Siakantu   +2 more
doaj   +1 more source

Biologically Active Implants Prevent Mortality in a Mouse Sepsis Model

open access: yesAdvanced Healthcare Materials, EarlyView.
A modular, triple‐action titanium implant is developed to prevent implant‐associated infections by repelling bacteria, killing pathogens, and enhancing tissue integration. Coatings with phage cocktails targeting P. aeruginosa and S. aureus show significant bacterial reduction and improved survival in a mouse sepsis model.
Martin Stark   +9 more
wiley   +1 more source

Experimental and Mathematical Optimization of a Pooling Test for Detection of SARS-CoV-2 in a Population with Low Viral Load

open access: gold, 2021
Hyeongseok Jeong   +6 more
openalex   +1 more source

A Human Kidney Tubuloid Model of Repeated Cisplatin‐Induced Cellular Senescence and Fibrosis for Drug Screening

open access: yesAdvanced Healthcare Materials, EarlyView.
Replicating aging and senescence‐related pathophysiological responses in kidney organoids remains a significant challenge. Human adult renal tubular organoid, tubuloids, are successfully developed recapitulating cellular senescence that is the central pathophysiological mechanism of chronic kidney disease (CKD).
Yuki Nakao   +20 more
wiley   +1 more source

An Innovative “Tooth‐On‐Chip” Microfluidic Device Emulating the Structure and Physiology of the Dental Pulp Tissue

open access: yesAdvanced Healthcare Materials, EarlyView.
This work presents a “tooth‐on‐chip” device that mimics dental pulp tissue. By co‐culturing key cell types, it recreates vascular networks, stem cell niches, the odontoblast/dentine interface, and trigeminal innervation. This innovative platform provides a unique model of dental pulp structure and physiology, with significant potential for accelerating
Alessandro Cordiale   +6 more
wiley   +1 more source

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