Results 281 to 290 of about 436,526 (334)

Evaluating the accuracy of HIV-1 viral load testing using near point of care Xpert HIV-1 system at Solwezi general hospital, Zambia. [PDF]

BMC Res Notes
Siakantu K, Chisompola D, Konzani AT.
europepmc   +1 more source

Breaking the Selectivity Barrier of Single‐Atom Nanozymes Through Out‐of‐Plane Ligand Coordination

Advanced Materials, EarlyView.
Here, Ru SAzyme with out‐of‐plane chlorine ligands is reported as a monofunctional, high‐performance peroxidase‐like nanozyme. Incorporating out‐of‐plane ligand coordination emulates enzyme selectivity and regulates reaction pathways for an identical substrate.
Seonhye Park, Kyu In Shim, Phuong Thy Nguyen, Daeeun Choi, Seongbeen Kim, Seung Yeop Yi, Moon Il Kim, Jeong Woo Han, Jinwoo Lee   +8 more
wiley   +1 more source

Rational Development of a Novel Emulgel Adjuvant for Single‐Shot Effective Vaccination: A Multivariate Analysis Approach

Advanced Materials, EarlyView.
Using multivariate analysis, a novel emulgel adjuvant is developed by combining key nanoemulsion formulation variables–hydrogel trapping, small globule size, and mannide monooleate surfactant–achieving 10× greater immunogenicity than MF59 in mice after a single shot.
Ahmed O. Shalash, Waleed M. Hussein, Ummey J. Nahar, Jingwen Wang, Lantian Lu, Armira Azuar, Jolynn J. E. Kiong, Prashamsa Koirala, Zeinab G. Khalil, Istvan Toth   +9 more
wiley   +1 more source

Pharmacokinetic/Pharmacodynamic Modelling and Monte Carlo Simulations to Predict Cytomegalovirus Viral Load in Pediatric Transplant Recipients Treated with (val)Ganciclovir. [PDF]

Clin Pharmacokinet
Koloskoff K, Franck B, Benito S, Welzel J, Autmizguine J, Theoret Y, Briand A, Ovetchkine P, Woillard JB.   +8 more
europepmc   +1 more source

Carbon Quantum Dots Assisted Virus Tracking: From Skin to Brain

Advanced Materials, EarlyView.
A novel carbon quantum dots‐dissolvable microneedle, CQDs‐dMN system, enables painless delivery and real‐time tracking of HSV‐1. The HSV‐1 is labeled with fluorescent CQDs and delivered to the skin dermis, minimizing damage compared to traditional methods.
Yaxiu Feng, Xiong Wang, Cien Chen, Di Wang, Changshun Hou, Yiran Wang, Huan Hu, Peiran Chen, LeiYing Qin, Qianya Wan, Xi Yao, Ming‐Liang He   +11 more
wiley   +1 more source

Study on the detection rate, genetic polymorphism, viral load, persistent infection capacity, and pathogenicity of human papillomavirus type 33. [PDF]

Virol J
Li Q, Cheng Q, Tian D, An Z, Li L, Yang F, Zhang M, Liu G, Peixin A, Yang Y, Chen Z.   +10 more
europepmc   +1 more source

Advances and Strategies in Enhancing mRNA Cancer Vaccines

Advanced Materials, EarlyView.
Messenger RNA (mRNA) vaccines offer a powerful approach for cancer immunotherapy, but their clinical impact remains limited by delivery challenges and suboptimal immune activation. This review discusses key biological barriers and design strategies—including structural optimization, immunomodulation, organ targeting delivery, and advanced nanocarriers ...
Miao Zhang, Shengqi Chen, Haijun Hu, Yenhui Ong, Qianqian Ni   +4 more
wiley   +1 more source

Host-Strain-Specific Responses to Pneumonia Virus of Mice Infection: A Study of Lesions, Viral Load, and Cytokine Expression. [PDF]

Viruses
Levy E, Gilliaux G, Sarlet M, Desmecht D, Van Laere AS.   +4 more
europepmc   +1 more source

Spatially Controlled 3‐D Multiplexed Aptamer Patterning in Hydrogels

Advanced Materials Interfaces, EarlyView.
A hydrogel platform based on norbornene‐functionalized polyvinyl alcohol enables high‐resolution, 3‐D multiplexed patterning of DNA aptamers via two‐photon polymerization. Two distinct aptamers are covalently immobilized with single micron‐scale precision across the x, y, and z dimensions.
Kevin Roost, Annina Stuber, Kongchang Wei, Marine de Lapeyrière, Ke Yang, Valentin Gantenbein, Salvador Pané, Ivan Corbeski, Katharina Maniura‐Weber, Nako Nakatsuka   +9 more
wiley   +1 more source

Can viral load predict a symptomatic congenital CMV infection? A systematic review and meta-analysis. [PDF]

Eur J Pediatr
Salomè S, Gammella R, Coppola C, Dolce P, Capasso L, Blázquez-Gamero D, Raimondi F.   +6 more
europepmc   +1 more source