Results 291 to 300 of about 365,069 (327)

Exploring AAV‐Mediated Gene Therapy for Inner Ear Diseases: from Preclinical Success to Clinical Potential

open access: yesAdvanced Science, EarlyView.
Current preclinical studies of AAV‐mediated gene therapy explore different strategies based on the characteristics of inner ear diseases. For genetic hearing loss, approaches include the replacement of a “good gene,” removal of a “bad gene,” or direct correction of mutations through base editing.
Fan Wu   +7 more
wiley   +1 more source

AAVR Expression is Essential for AAV Vector Transduction in Sensory Hair Cells

open access: yesAdvanced Science, EarlyView.
Decreased sensitivity to AAV vector transduction in the outer hair cells (OHCs) of adult mice is primarily attributed to reduction of AAVR (Kiaa0319l; Au040320). Knockout of AAVR reduces AAV vector transduction efficiency in both inner hair cells (IHCs) and OHCs in neonatal mice.
Fan Wu   +8 more
wiley   +1 more source

Factors associated with viral load suppression in pregnant and postpartum women living with HIV in Rwanda: an open-observational cohort study. [PDF]

open access: yesFront Public Health
Munyaneza A   +11 more
europepmc   +1 more source

Face mask use and viral load in patients with mild symptoms of COVID-19. [PDF]

open access: yesEinstein (Sao Paulo)
Costa MS   +11 more
europepmc   +1 more source

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