Current preclinical studies of AAV‐mediated gene therapy explore different strategies based on the characteristics of inner ear diseases. For genetic hearing loss, approaches include the replacement of a “good gene,” removal of a “bad gene,” or direct correction of mutations through base editing.
Fan Wu+7 more
wiley +1 more source
Evaluation of the performance of a qPCR-based assay for HIV-1 viral load determination. [PDF]
Lin B, Han C, Li JH, Wang R.
europepmc +1 more source
AAVR Expression is Essential for AAV Vector Transduction in Sensory Hair Cells
Decreased sensitivity to AAV vector transduction in the outer hair cells (OHCs) of adult mice is primarily attributed to reduction of AAVR (Kiaa0319l; Au040320). Knockout of AAVR reduces AAV vector transduction efficiency in both inner hair cells (IHCs) and OHCs in neonatal mice.
Fan Wu+8 more
wiley +1 more source
Factors associated with viral load suppression in pregnant and postpartum women living with HIV in Rwanda: an open-observational cohort study. [PDF]
Munyaneza A+11 more
europepmc +1 more source
Prevalence of detectable viral load and its associated factors among adult patients receiving ART in Choma District, Zambia. [PDF]
Mutukwa M+4 more
europepmc +1 more source
Face mask use and viral load in patients with mild symptoms of COVID-19. [PDF]
Costa MS+11 more
europepmc +1 more source
Robustness of viral load over CD4 cell count in measuring the quality of life of people with HIV at second line regimen in Amhara region. [PDF]
Tegegne AS.
europepmc +1 more source
Estimating Mean Viral Load Trajectory From Intermittent Longitudinal Data and Unknown Time Origins. [PDF]
Woodbridge Y+3 more
europepmc +1 more source