Results 341 to 350 of about 3,712,649 (404)

Longitudinal Viral Load Clustering for People With HIV Using Functional Principal Component Analysis. [PDF]

AIDS Res Treat
Ma Y, Yang X, Xiao J, Li X, Olatosi B, Zhang J.   +5 more
europepmc   +1 more source

Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation

Advanced Science, EarlyView.
At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao, Jiayu Lu, Quanjun Yang, Zhenqi Liu, Cuiping Wu, Bingbing Ke, Kaiyan Su, Haolin Yuan, Yaqi Cui, Yao Wang, Richard Salvi, Guang Yang, Shankai Yin, Feng Liu, Chunyan Li   +14 more
wiley   +1 more source

Reducing the viral load while securing the airway

Journal of Anaesthesiology Clinical Pharmacology, 2020
openaire   +4 more sources

RONIN/HCF1‐TFEB Axis Protects Against D‐Galactose‐Induced Cochlear Hair Cell Senescence Through Autophagy Activation

Advanced Science, EarlyView.
D‐galactose (D‐gal) induced inner ear hair cell senescence by inhibiting TFEB transcription. RONIN/HCF1 promotes TFEB transcription to prevent cochlear HCs from D‐gal‐induced senescence through autophagy activation. Abstract Age‐related hearing loss is characterized by senescent inner ear hair cells (HCs) and reduced autophagy.
Yongjie Wei, Yuhua Zhang, Wei Cao, Nan Cheng, Yun Xiao, Yongjun Zhu, Yan Xu, Lei Zhang, Lingna Guo, Jun Song, Su‐hua Sha, Buwei Shao, Fang Ma, Jingwen Yang, Zheng Ying, Zuhong He, Renjie Chai, Qiaojun Fang, Jianming Yang   +18 more
wiley   +1 more source

Study on the clinical characteristics, persistent infection capability, and viral load of human papillomavirus type 82 single infection. [PDF]

Virol J
Chen Z, Cheng Q, Zhang X, Tao F, Li N, Liu G, Mu X, Zhang M, Dong Z, Li Q.   +9 more
europepmc   +1 more source

AAVR Expression is Essential for AAV Vector Transduction in Sensory Hair Cells

Advanced Science, EarlyView.
Decreased sensitivity to AAV vector transduction in the outer hair cells (OHCs) of adult mice is primarily attributed to reduction of AAVR (Kiaa0319l; Au040320). Knockout of AAVR reduces AAV vector transduction efficiency in both inner hair cells (IHCs) and OHCs in neonatal mice.
Fan Wu, Guisheng Chen, Rui Hu, Peiwen Liu, Jintao Lou, Wenji Zhao, Zuhong He, Suhua Sha, Yiqing Zheng   +8 more
wiley   +1 more source

Factors associated with viral load re-suppression after enhanced adherence counseling among people living with HIV with an initial high viral load result in selected Nigerian states. [PDF]

PLOS Glob Public Health
Obasa GB, Ijaiya M, Okwor E, Dare B, Emerenini F, Oladigbolu R, Anyanwu P, Akinjeji A, Brickson K, Zech J, Ogundare Y, Atuma E, Strachan M, Fayorsey R, Curran K.   +14 more
europepmc   +1 more source

Efavirenz as a Substitute for Protease Inhibitors in HIV-1–Infected Patients With Undetectable Plasma Viral Load on HAART: A Median Follow-Up of 64 Weeks

, 2001
David Rey, Marie‐Paule Schmitt, Marialuisa Partisani, Georgette Hess-Kempf, Véronique Krantz, Erik de Mautort, Claudine Bernard-Henry, Michèle Priester, Christine Cheneau, Jean-Marie Lang   +9 more
openalex   +1 more source

Microbiome Single Cell Atlases Generated with a Commercial Instrument

Advanced Science, EarlyView.
Single cell sequencing is valuable for dissecting complex systems and uncovering unique features in individual cell types. However, tools for single cell microbial analysis are limited. Easily Accessible Single microbe sequencing (EASi‐seq), which adapts a commercially available single cell platform for efficient sequencing of single microbial genomes ...
Xiangpeng Li, Linfeng Xu, Benjamin Demaree, Cecilia Noecker, Jordan E. Bisanz, Daniel W. Weisgerber, Cyrus Modavi, Peter J. Turnbaugh, Adam R. Abate   +8 more
wiley   +1 more source

Evaluating HPV Viral Load and Multiple Infections for Enhanced Cervical Cancer Risk-Based Assessment. [PDF]

Life (Basel)
Varesano S, Ciccarese G, Paudice M, Mazzocco K, Gaggero G, Ferrero S, Icardi G, Vellone VG.   +7 more
europepmc   +1 more source