Results 71 to 80 of about 3,717,929 (382)

Association between upper respiratory tract viral load, comorbidities, disease severity and outcome of patients with SARS-CoV-2 infection

Journal of Infectious Diseases, 2021
Background There is limited information on the association between upper respiratory tract (URT) viral loads, host factors, and disease severity in SARS-CoV-2 infected patients. Methods We studied 1,122 patients (mean age: 46 years) diagnosed by PCR. URT
H. Maltezou, V. Raftopoulos, R. Vorou, K. Papadima, K. Mellou, N. Spanakis, A. Kossyvakis, G. Gioula, M. Exindari, Elisavet Froukala, B. Martinez-Gonzalez, G. Panayiotakopoulos, A. Papa, A. Mentis, A. Tsakris   +14 more
semanticscholar   +1 more source

The role of coinfections in HIV epidemic trajectory and positive prevention: a systematic review and meta-analysis. [PDF]

, 2011
OBJECTIVES: Recurrent or persistent coinfections may increase HIV viral load and, consequently, risk of HIV transmission, thus increasing HIV incidence.
Baeten, Baeten, Barbour, Bunnell, Cachay, Cachay, Celum, Chen, Chu, Day, Dean, Del Amo, Delany, Donnell, Duffus, Dunne, Egger, Fraser, French, Glynn, Goletti, Gray, Grimwade, Hewitt, Higgins, Hoffman, Hung, Kalou, Kizza, Kublin, Lawn, Liberati, Lingappa, Lingappa, Lopez-Gatell, Manoff, Mawa, Mayaud, Modjarrad, Modjarrad, Mole, Morris, Nagot, Nikolaeva, Paz-Bailey, Phiri, Quinn, Renia, Schacker, Schon, Serwadda, Slutsker, Straetemans, Swaminathan, Tanton, Tatfeng, Toossi, Toossi, Van Geertruyden, Wallis, Walson, Whalen, Zhu, Zuckerman, Zuckerman   +64 more
core   +1 more source

Level of viral load suppression in Rwinkwavu District Hospital: A cross-sectional study

Journal of Interventional Epidemiology and Public Health
Introduction: The Rwinkwavu district hospital faces challenges in understanding and improving the human immunodeficiency virus viral load suppression rates among patients receiving antiretroviral therapy.
Metuschelah Habimana, Rachel Niyogushimwa, Vedaste Ndahindwa, Theoneste Ntakirutimana   +3 more
doaj   +1 more source

Prevalence and predictors of viral load suppression in adults living with HIV in the western region of Ghana: A cross-sectional study

AIMS Public Health, 2023
Background: Although antiretroviral therapy is beneficial and available free of cost to patients, several roadblocks still prevent patients from reaching viral suppression.
Philip Boakye, Adwoa Safowaa
doaj   +1 more source

Effectiveness of highly active antiretroviral therapy in HIV-positive children: evaluation at 12 months in a routine program in Cambodia. [PDF]

, 2007
OBJECTIVE: Increasing access to highly active antiretroviral therapy to reach all those in need in developing countries (scale up) is slowly expanding to HIV-positive children, but documented experience remains limited. We aimed to describe the clinical,
Akao, K, Ford, N, Gupta, J, Janssens, B, Nerrienet, E, Nouhin, J, Raleigh, B, Soeung, S, Te, V, Vun, M   +9 more
core   +2 more sources

The pulmonary-proteoliposome as a new therapeutic approach for Coronaviruses [PDF]

, 2020
We are proposing the use of pulmonary-proteoliposome as a new therapeutic approach for Coronaviruses. The designed strategy represents a potential treatment to reduce the overall viral load in the lungs and to help the immune system to successfully stave
Feliciello, Isidoro, Procino, Alfredo
core   +1 more source

Prognostic value of severe acute respiratory syndrome coronavirus‐2 viral load and antibodies in patients hospitalized with COVID‐19

Clinical and Translational Science, 2023
Observational studies have identified the potential prognostic value for severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) viral load and anti‐SARS‐CoV‐2 antibodies in coronavirus disease 2019 (COVID‐19). However, viral load in nasopharyngeal (
Rebecca N. Bauer, Anastasia Teterina, Haridha Shivram, Jacqueline McBride, Carrie M. Rosenberger, Fang Cai, Min Bao, Larry Tsai, Oliver Gordon, Ivan T. Lee, Jeffrey J. Wallin, Danielle Porter, Kavita Juneja, Gregory Camus, Ivan O. Rosas, Steffen Wildum   +15 more
doaj   +1 more source

Variation in HIV-1 set-point viral load: epidemiological analysis and an evolutionary hypothesis.

, 2007
The natural course of HIV-1 infection is characterized by a high degree of heterogeneity in viral load, not just within patients over time, but also between patients, especially during the asymptomatic stage of infection.
Chapman, Ruth, de Wolf, Frank, Fraser, Christophe, Hanage, William P, Hollingsworth, T Déirdre   +4 more
core   +2 more sources

Waning of SARS-CoV-2 booster viral-load reduction effectiveness

Nature Communications, 2021
The BNT162b2 COVID-19 vaccine has been shown to reduce viral load of breakthrough infections (BTIs), an important factor affecting infectiousness. This viral-load protective effect has been waning with time post the second vaccine and later restored with
M. Levine-Tiefenbrun, I. Yelin, H. Alapi, E. Herzel, Jacob Kuint, G. Chodick, S. Gazit, T. Patalon, R. Kishony   +8 more
semanticscholar   +1 more source

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

FEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali, Gloria Giacomello, Michela Vuono, Silvia Gregori   +3 more
wiley   +1 more source