Results 121 to 130 of about 102,673 (134)

Implications of Tobacco Use on Pathogen‐Driven Diseases: A Public Health and Policy Perspective

World Medical &Health Policy, EarlyView.
ABSTRACT The tobacco epidemic remains one of the most significant global public health challenges, responsible for over 8 million deaths annually, with a substantial portion occurring among non‐smokers exposed to second‐hand smoke. While cigarette smoking remains the most prevalent form of tobacco use worldwide, the rise of electronic nicotine delivery
Nadine Kabbani, James L. Olds
wiley   +1 more source

Real‐world safety and effectiveness of guselkumab in patients with psoriasis: A post‐marketing surveillance study through up to week 52 in Japan

The Journal of Dermatology, EarlyView.
Abstract Guselkumab is a monoclonal antibody that binds to the p19 subunit of interleukin‐23 and inhibits its downstream signaling. The safety profile of guselkumab and its superior efficacy over placebo and adalimumab for the treatment of patients with moderate‐to‐severe psoriasis were reported in phase 3 studies conducted within and outside Japan. To
Yayoi Tada, Yukako Sugiura, Manami Kamishima, Shoya Takahashi, Yoshihito Tanaka, Junya Masuda, Keiichi Yamanaka   +6 more
wiley   +1 more source

Clinical decision instruments for predicting mortality in patients with cirrhosis seeking emergency department care

Academic Emergency Medicine, EarlyView.
Abstract Objective Clinical decision instruments (CDIs) could be useful to aid risk stratification and disposition of emergency department (ED) patients with cirrhosis. Our primary objective was to derive and internally validate a novel Cirrhosis Risk Instrument for Stratifying Post‐Emergency department mortality (CRISPE) for the outcomes of 14‐ and 30‐
Swetha Parvataneni, Michelle Haugh, Yara Sarkis, Brittany Baker, Lauren D. Nephew, Marwan S. Ghabril, Raj Vuppalanchi, Eric S. Orman, Naga P. Chalasani, Archita P. Desai, Nicholas Eric Harrison   +10 more
wiley   +1 more source

Effect of host‐protein test (TRAIL/IP‐10/CRP) on antibiotic prescription and emergency department or urgent care center return visits: The JUNO pilot randomized controlled trial

Academic Emergency Medicine, EarlyView.
Abstract Objectives Determining etiology for adults with symptoms of lower respiratory tract infection (LRTI) is challenging. MeMed BV (MMBV), an FDA‐cleared blood test, computationally integrates the levels of three host proteins to differentiate bacterial and viral infections.
Adam J. Singer, Judd E. Hollander, Efrat R. Kean, Hope Ring, W. Frank Peacock, Karina M. Soto‐Ruiz, Sergey Motov, Joby Thoppil, Phyllis Hendry, Salim Halabi, Andrew C. Meltzer, Gary F. Headden, Tal Brosh‐Nissimov, David Zeltser, Chad M. Cannon   +14 more
wiley   +1 more source

Wound, pressure ulcer, and burn guidelines (2023)―4: Guidelines for the management of connective tissue disease/vasculitis‐associated skin ulcers, third edition

The Journal of Dermatology, EarlyView.
Yoshihide Asano, Jun Asai, Takayuki Ishii, Yohei Iwata, Masanari Kodera, Chie Miyabe, Akihiko Uchiyama, Youichi Ogawa, Ken Okamura, Mari Kishibe, Yuta Koike, Yorihisa Kotobuki, Noriki Fujimoto, Takuya Miyagi, Yukie Yamaguchi, Ayumi Yoshizaki, Reiko Omori, Takeshi Nakanishi, Hiroshi Fujiwara, Takeo Maekawa, Sei‐ichiro Motegi, Yuichiro Yoshino, Minoru Hasegawa, Manabu Fujimoto, Takao Tachibana, Wound, Pressure Ulcer, and Burn Guidelines Drafting Committee (connective tissue disease/vasculitis group)   +27 more
wiley   +1 more source

High‐flow nasal cannula oxygen therapy for children with bronchiolitis: Implementation of a national guideline

Acta Paediatrica, EarlyView.
Abstract Aim High flow nasal cannula (HFNC) therapy is a form of respiratory support used in children with bronchiolitis. A national guideline for the use of HFNC was published in The Netherlands in 2020. We studied the implementation and use of this guideline.
Nike Beckeringh, Rosalie S. N. Linssen, Berber Kapitein, Job B. M. van Woensel, Frans B. Plötz, Pediatric Research and Evaluation Network (PREN) Amsterdam study group, M. Bijlsma, M. Felderhof, J. Hol, M. van Houten, A. van Kempen, F. Nauta, N. Oeij, N. Ran, M. Rijpert, G.W. ten Tusscher   +15 more
wiley   +1 more source

Finnish nationwide controlled register study found increased inpatient infections in children with 22q11.2 deletion syndrome

Acta Paediatrica, EarlyView.
Abstract Aim Studies on treating infections in children with 22q11.2 deletion syndrome (22q11.2DS) have been limited. We characterised inpatient infections and outpatient antibiotic treatment. Methods Children born during 2005–2018 were eligible for this national Finnish retrospective register‐based study.
Sakari Wahrmann, Leena Kainulainen, Johanna Lempainen, Ville Kytö   +3 more
wiley   +1 more source

Children With Sydenham Chorea and Psychiatric Disorders Had Variable Long‐Term Outcomes and Required Multidisciplinary Management

Acta Paediatrica, EarlyView.
ABSTRACT Aim Sydenham chorea (SC) is a globally significant, post‐streptococcal, childhood neuropsychiatric condition that is rare in western Europe. This retrospective single‐centre study focused on children with neuropsychiatric features of SC. Methods Participants were recruited from neuropsychiatry referrals to a regional paediatric neurology ...
Nadine Mushet, Michael Morton, Helen Minnis, Christopher Gillberg   +3 more
wiley   +1 more source

Causes of mortality in koalas autopsied at the University of Melbourne

Australian Veterinary Journal, EarlyView.
Objective To determine the causes of mortality in koalas autopsied at the University of Melbourne based on the retrospective analysis of autopsy reports. Methods The autopsy reports of 239 koalas examined at the University of Melbourne from 1970 to 2023 were reviewed to determine which of the comorbidities present was the primary cause to which death ...
L Wilson, P Whiteley, A Stent, F Stockman, F Elloy, EC Hobbs, VG Astudillo, KVF Jubb, P Loukopoulos   +8 more
wiley   +1 more source

Challenges for the improvement of valganciclovir prophylaxis in solid organ transplantation and the possible role of therapeutic drug monitoring in adults

British Journal of Clinical Pharmacology, EarlyView.
Cytomegalovirus (CMV) infection frequently occurs after solid organ transplantation and is associated with an increased morbidity and mortality. Fortunately, the development of valganciclovir prophylaxis has lowered the incidence of CMV infection and its complications in immunosuppressed solid organ transplant recipients.
Lukas K. van Vugt, Dennis A. Hesselink, Brenda C. M. de Winter   +2 more
wiley   +1 more source