Results 131 to 134 of about 102,673 (134)
Long‐term outcome after allogeneic stem cell transplantation for GATA2 deficiency: An analysis of 67 adults and children from France and Belgium
British Journal of Haematology, EarlyView.The overall survival of patients receiving an allogeneic haematopoietic stem cell transplant (HSCT) for GATA2 deficiency was significantly better if they were transplanted recently, with a bone marrow or cord blood graft and if the transplant was performed before the onset of excess blast. Excess blast before HSCT was the only factor associated with an Flore Sicre de Fontbrune, Florian Chevillon, Mony Fahd, Kristell Desseaux, Xavier Poiré, Edouard Forcade, Arthur Sterin, Bénédicte Neven, Virginie Gandemer, Sylvain Thepot, Alice Garnier, Bruno Lioure, Ambroise Marcais, Stephanie Nguyen‐Quoc, Suzanne Tavitian, Laure Vincent, Jean Donadieu, Matthieu Resche Riggon, Sylvie Chevret, Marlene Pasquet, Regis Peffault de Latour +20 morewiley +1 more sourceAirway Basal Stem Cells Inflammatory Alterations in COVID‐19 and Mitigation by Mesenchymal Stem Cells
Cell Proliferation, EarlyView.Airway basal stem cells derived from COVID‐19 patients demonstrated pronounced goblet cell hyperplasia, inflammatory responses and tendencies toward fibrosis. Co‐culture with mesenchymal stem cells (MSCs) notably reduced these pathological changes, likely due to MSCs' regulatory effects on the interferon signalling pathway.Sheng Du, Jing Jin, Chunli Tang, Zhuquan Su, Lulin Wang, Xinyuan Chen, Mengni Zhang, Yiping Zhu, Jiaojiao Wang, Chunrong Ju, Xinyu Song, Shiyue Li +11 morewiley +1 more sourceSuper‐Enhancer Target Gene CBP/p300‐Interacting Transactivator With Glu/Asp‐Rich C‐Terminal Domain, 2 Cooperates With Transcription Factor Forkhead Box J3 to Inhibit Pulmonary Vascular Remodeling
Cell Proliferation, EarlyView.During hypoxia, the transcriptional effect of super‐enhancer in promoting CBP/p300‐interacting transactivator with Glu/Asp‐rich C‐terminal domain, 2 reduced, eventually leading to the thickening of the smooth muscle layer of the pulmonary artery.Songyue Li, Jingya Zhang, Xu Wang, Xinru Wang, Yuyu Song, Xinyue Song, Xiuli Wang, Weiwei Cao, Chong Zhao, Jing Qi, Xiaodong Zheng, Yan Xing +11 morewiley +1 more source