Results 311 to 320 of about 1,311,115 (388)

Treatment strategies with combined agency against severe viral pneumonia in patients with advanced cancer. [PDF]

J Transl Int Med
Zhang F, Li T, Bai Y, Liu J, Qin J, Wang A, Zhu Y, Zhang M, Ma Z, Zhou X, Wang L, Gao M, Wu X, Shao Y, Zhao X, Wen J, Guan J, Wang J, Ma J, Tao H, Hu Y.   +20 more
europepmc   +1 more source

Allogeneic transplantation after failure of chimeric antigen receptor‐T cells and exposure to bispecific antibodies: Feasibility, safety and survival outcomes

British Journal of Haematology, EarlyView.
Summary Clinical outcome after chimeric antigen receptor (CAR)‐T‐cell failure in large B‐cell lymphoma (LBCL) is dismal. Allogeneic stem cell transplantation (alloSCT) represents a potentially curative salvage for relapsed/refractory LBCL, although concerns remain regarding its feasibility and safety in patients exposed to CAR‐T and bispecific ...
Angelica Barone, Chiara De Philippis, Federico Stella, Anna Dodero, Barbara Sarina, Martina Pennisi, Armando Santoro, Carmelo Carlo‐Stella, Anna Guidetti, Stefania Bramanti, Paolo Corradini   +10 more
wiley   +1 more source

Vascular endothelial-derived SPARCL1 exacerbates viral pneumonia through pro-inflammatory macrophage activation. [PDF]

Nat Commun
Zhao G, Gentile ME, Xue L, Cosgriff CV, Weiner AI, Adams-Tzivelekidis S, Wong J, Li X, Kass-Gergi S, Holcomb NP, Basal MC, Stewart KM, Planer JD, Cantu E, Christie JD, Crespo MM, Mitchell MJ, Meyer NJ, Vaughan AE.   +18 more
europepmc   +1 more source

CD123‐targeting immunotherapeutic approaches in acute myeloid leukaemia

British Journal of Haematology, EarlyView.
Summary Treatment of relapsed or refractory acute myeloid leukaemia (AML) has remained a significant challenge, with limited available targeted immunotherapies. CD123, or the interleukin‐3 (IL‐3) receptor, has long been known as a potential target expressed on AML blasts, and a range of different approaches to targeting CD123 have been trialled with ...
Alexandra Dreyzin, Noa G. Holtzman, Challice L. Bonifant   +2 more
wiley   +1 more source

Material basis and pharmacodynamic mechanism of YangshenDingzhi granules in the intervention of viral pneumonia: Based on serum pharmacochemistry and network pharmacology. [PDF]

Animal Model Exp Med
Xu H, Dong M, Du R, Zhang C, Chen Z, Tian G, Cui Q, Li K.   +7 more
europepmc   +1 more source

Viral pneumonia and pulmonary alveolar proteinosis: the cause and the effect, case report

, 2019
Saeed Albogami, Abdelfattah Touman
openalex   +1 more source

Dysregulation of the endosomal sorting complex III is linked to neurodegeneration in progressive multiple sclerosis

Brain Pathology, EarlyView.
This study shows that components of the ESCRT‐III membrane repair machinery, VPS4B and CHMP2A, are dysregulated in progressive MS and are associated with higher neurodegeneration and inflammation. This might lead to improper function of the complex to inhibit the final stages of necroptosis activation and thus impede neuronal cell death.
Carmen Picon, Robertas Aleksynas, Marcelina Wojewska, Francesco de Virgiliis, Doron Merkler, Richard Reynolds   +5 more
wiley   +1 more source

One-Year Survival and Hospital-free Days in Critical Illness After Viral Pneumonia. [PDF]

Am J Respir Crit Care Med
Atramont A, Martin GL, Singer M, Tajahmady A, Agamaliyev E, Harhay MO, Leone M, Legrand M.   +7 more
europepmc   +1 more source

Super‐Enhancer Target Gene CBP/p300‐Interacting Transactivator With Glu/Asp‐Rich C‐Terminal Domain, 2 Cooperates With Transcription Factor Forkhead Box J3 to Inhibit Pulmonary Vascular Remodeling

Cell Proliferation, EarlyView.
During hypoxia, the transcriptional effect of super‐enhancer in promoting CBP/p300‐interacting transactivator with Glu/Asp‐rich C‐terminal domain, 2 reduced, eventually leading to the thickening of the smooth muscle layer of the pulmonary artery.
Songyue Li, Jingya Zhang, Xu Wang, Xinru Wang, Yuyu Song, Xinyue Song, Xiuli Wang, Weiwei Cao, Chong Zhao, Jing Qi, Xiaodong Zheng, Yan Xing   +11 more
wiley   +1 more source

Precision treatment of viral pneumonia through macrophage-targeted lipid nanoparticle delivery. [PDF]

Proc Natl Acad Sci U S A
Zhao G, Xue L, Geisler HC, Xu J, Li X, Mitchell MJ, Vaughan AE.   +6 more
europepmc   +1 more source