Results 71 to 80 of about 317,906 (338)
Here it is revealed that the costimulatory receptors CD27 and ICOS are essential for the long‐term maintenance of PD‐1high CD8+ TRM cells following influenza infection. PD‐L1 blockade enhances the proliferation and activation of these cells through Nur77 activation downstream of the CD27/ICOS signaling axis, thereby boosting host immunity against ...
Yuanyuan Chen +16 more
wiley +1 more source
Investigation into the Causes and Severity of the 1918 Influenza Pandemic [PDF]
The 1918 Influenza outbreak is regarded as one of the worst pandemics in human history due to its widespread effects across the globe and its high death rate.
Freedenberg, Alex T.
core +1 more source
Principles of appropriate antibiotic use for treatment of uncomplicated acute bronchitis: background. [PDF]
The following principles of appropriate antibiotic use for adults with acute bronchitis apply to immunocompetent adults without complicating comorbid conditions, such as chronic lung or heart disease.
Bartlett, JG +7 more
core +2 more sources
Severe COVID-19 pneumonia in an intensive care setting and comparisons with historic severe viral pneumonia due to other viruses [PDF]
Kiran Dadhwal +4 more
openalex +1 more source
This study demonstrates that BNNT exposure disrupts lipid homeostasis in bronchial epithelial cell cultures and activates eicosanoid lipid biosynthesis, producing inflammatory lipid mediators like leukotrienes. These effects are more pronounced in asthmatic cell cultures compared to healthy ones.
Govind Gupta +14 more
wiley +1 more source
Objective: to evaluate the clinical and radiological features of viral pneumonia caused by influenza A (H1N1) in 2015–2016.Material and methods. The study involved 22 patients (13 men, 9 women, 1 patient died) with viral pneumonia caused by influenza A ...
A. A. Speranskaia +3 more
doaj +1 more source
On the use of clustering and the MeSH controlled vocabulary to improve MEDLINE abstract search [PDF]
Databases of genomic documents contain substantial amounts of structured information in addition to the texts of titles and abstracts. Unstructured information retrieval techniques fail to take advantage of the structured information available.
Blott, Stephen +3 more
core
Respiratory syncytial virus: Clinical and epidemiological pattern in pediatric patients admitted to a children’s hospital between 2000 and 2013 [PDF]
INTRODUCTION: Respiratory syncytial virus (RSV) is the major causative organism associated with acute lower respiratory tract infections in children.The objective of this study was to describe the clinical and epidemiological pattern of RSV and identify ...
Bakir, Julia +8 more
core +1 more source
Initial PCR Testing Negative, but Chest CT Suggesting for Viral Pneumonia Urges for Repeated Testing for COVID-19 Diagnosis [PDF]
Lingwei Wang +11 more
openalex +1 more source
In Parkinson's disease, SHMT1 downregulation disrupts its interaction with PEMT in astrocytes, reducing SAM levels. This leads to H3K4me1 hypomethylation and decreased Slc1a2/Glul expression, ultimately exacerbating neuroexcitotoxicity and dopaminergic neuron loss.
Yue‐Han Chen +17 more
wiley +1 more source

