Results 131 to 140 of about 370,832 (346)
microRNAs in viral acute respiratory infections: immune regulation, biomarkers, therapy, and vaccines [PDF]
Stephen Adonai Leon‐Icaza +2 more
openalex +1 more source
Single‐Cell Insights Into Macrophage Subtypes in Pulmonary Infections
This review highlights the dynamic plasticity of macrophages during pulmonary infections and proposes an integrative framework defining six functional subtypes: Inflam‐Ms, Hub‐Ms, Reg‐Ms, Prolif‐Ms, Memory‐Ms, and Senesc‐Ms. Single‐cell omics delineate their distinct roles in homeostasis and infection, refining our understanding of macrophage ...
Zhaoheng Lin +3 more
wiley +1 more source
A comprehensive insight on the challenges for COVID-19 vaccine: A lesson learnt from other viral vaccines. [PDF]
Singh RS +13 more
europepmc +1 more source
Zika viral proteome analysis reveals an epitope cluster within NS3 helicase as a potential vaccine candidate: anin silicostudy [PDF]
Md Tangigul Haque +4 more
openalex +1 more source
2320. Novel checkpoint modifier lowers T cell activation threshold and enhances and broadens vaccine-induced responses to chronic viral infections [PDF]
Mohadeseh Hasanpourghadi +5 more
openalex +1 more source
This study designs a novel mRNA‐LNP vaccine targeting VZV glycoprotein E (gE) for herpes zoster via an AI‐assisted pipeline. Validated in mice and rhesus macaques, the mRNA‐LNP vaccine shows strong humoral and cellular immune responses, with CD4+ T‐cell responses more effective and durable than Shingrix, offering a promising prophylactic option ...
Kai Dong +6 more
wiley +1 more source
Effects of concurrent administration of modified live viral vaccines with RB51 on immune responses to RB51. [PDF]
Crawford L +4 more
europepmc +1 more source
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng +9 more
wiley +1 more source

