Results 161 to 170 of about 1,574,741 (371)

Towards an anti-viral vaccine for a human cancer [PDF]

, 1975
M. A. Epstein
openalex   +1 more source

CXCR3+ T Follicular Helper Cells Induced by Co-Administration of RTS,S/AS01B and Viral-Vectored Vaccines Are Associated With Reduced Immunogenicity and Efficacy Against Malaria

Frontiers in Immunology, 2018
A malaria vaccine strategy targeting multiple lifecycle stages may be required to achieve a high level of efficacy. In two Phase IIa clinical trials, we tested immunogenicity and efficacy of RTS,S/AS01B administered alone, in a staggered regimen with ...
Georgina S. Bowyer, Amy Grobbelaar, T. Rampling, N. Venkatraman, D. Morelle, R. Ballou, A. Hill, K. Ewer   +7 more
semanticscholar   +1 more source

The Non‐Canonical ChREBPα Activity Suppresses the Activation of Hepatic Stellate Cells and Liver Fibrosis by Antagonizing TGF‐β‐E2F1 Axis

Advanced Science, EarlyView.
Intrahepatic microenvironment greatly impacts duration and degree of HSCs activation and development of liver fibrosis. By inhibiting TGFβ‐E2F1‐driven production of profibrogenic factors (CTGF and THBS1), hepatocyte ChREBPα monitors hepatic microenvironment and suppresses the overactivation of HSCs.
Jian Zhang, Yuee Zhao, Gauthami Pulivendala, Qing Zhang, Liangyou Rui, Jiashi Gao, Huiwen Wang, Gary Zhang, Alli Nuotio‐Antar, Xin Tong, Lei Yin   +10 more
wiley   +1 more source

FREQUENCY OF DETECTION OF ANTIBODIES TO HEPATITIS C VIRUS AMONG CONVENTIONALLY HEALTHY POPULATION OF RUSSIAN FEDERATION

Журнал микробиологии, эпидемиологии и иммунобиологии, 2017
Aim. Determine the prevalence of antibodies to hepatitis C virus (anti-HCV) among conditionally healthy population of Russian Federation. Materials and methods.
N. V. Soboleva, A. A. Karlsen, T. V. Kozhanova, V. S. Kichatova, V. V. Klushkina, O. V. Isaeva, M. E. Ignatyeva, VV. .. Romanenko, N. D. Oorzhak, E. Yu. Malinnikova, K. K. Kyuregyan, M. I. Mikhaylov   +11 more
doaj   +1 more source

Bestatin, A Pluripotent Immunomodulatory Small Molecule, Drives Robust and Long-Lasting Immune Responses as an Adjuvant in Viral Vaccines. [PDF]

Vaccines (Basel), 2023
Kim HW, Ko MK, Park SH, Shin S, Kim SM, Park JH, Lee MJ.   +6 more
europepmc   +1 more source

Viral Inhibition of the IFN-Induced JAK/STAT Signalling Pathway: Development of Live Attenuated Vaccines by Mutation of Viral-Encoded IFN-Antagonists

Vaccines, 2016
The interferon (IFN) induced anti-viral response is amongst the earliest and most potent of the innate responses to fight viral infection. The induction of the Janus kinase/signal transducer and activation of transcription (JAK/STAT) signalling pathway ...
S. Fleming
semanticscholar   +1 more source

Advances in Single‐Cell Sequencing for Infectious Diseases: Progress and Perspectives

Advanced Science, EarlyView.
Single‐cell sequencing technologies uncover novel, unknown, and emergent features of many diseases. This review describes recent progress of single‐cell sequencing technologies and their applications in infectious diseases, summarizes the underlying commonalities of different infections and discusses future research directions, facilitating the ...
Mengyuan Lyu, Yang Liu, Jian Zhou, Hongli Lai, Hongxia Ruan, Dongsheng Wu, Shun Zhu, Xudong Zhou, Wananqi Ma, Yuchen Huang, Shuting Lei, Han Luo, Jie Chen, Binwu Ying   +13 more
wiley   +1 more source

Characterization of Endogenous Retroviral-like Particles Expressed from the Spodoptera frugiperda Sf9 Cell Line

Viruses
The Spodoptera frugiperda Sf9 insect cell line is used in the baculovirus expression vector system for the development of various viral vaccines and some gene therapy products.
Hailun Ma, Eunhae H. Bae, Pei-Ju Chin, Arifa S. Khan   +3 more
doaj   +1 more source

A comprehensive insight on the challenges for COVID-19 vaccine: A lesson learnt from other viral vaccines. [PDF]

Heliyon, 2023
Singh RS, Singh A, Masih GD, Batra G, Sharma AR, Joshi R, Prakash A, Suroy B, Sarma P, Prajapat M, Kaur H, Bhattacharyya A, Upadhyay S, Medhi B.   +13 more
europepmc   +1 more source

Vaccines '87: Modern Approaches to New Vaccines. Prevention of AIDS and Other Viral, Bacterial and Parasitic Diseases. Edited by R. M. Chanock, R. A. Lerner, F. Brown and H. Ginsberg. Cold Spring Harbor: Cold Spring Harbor Laboratory, New York. 1987. 461 pages. Paper, $95.00. ISBN 0 87969 302 9. [PDF]

, 1988
Robert G. Ridley
openalex   +1 more source