Results 211 to 220 of about 1,490,578 (344)

Optimizing the dengue virus infection mouse model: Comparing different backgrounds and infection route for enhanced stability

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Optimized dengue fever animal model: IFNAR−/− BALB/c mice with intraperitoneal injection. Background screening: Between IFNAR−/− (BALB/c, C57BL/6) and AG129 mice, IFNAR−/−BALB/c exhibited the most severe symptoms: (1) highest weight loss and clinical scores; (2) peak viremia (5.44 log10 RNA copies/mL, day 4); (3) significant organ damage (liver/brain ...
Dan Liao   +9 more
wiley   +1 more source

The Brighton Collaboration standardized template for collection of key information for benefit-risk assessment of inactivated viral vaccines. [PDF]

open access: yesVaccine, 2020
Kochhar S   +15 more
europepmc   +1 more source

Multimorbidity and animal models

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Multimorbidity, defined as the coexistence of ≥2 chronic conditions, is associated with aging, genetics, and environmental factors. Animal models in multimorbidity research span three tiers: simple organisms for initial screening → rodents for mechanistic analysis → large mammals for clinical prediction.
Xinpei Wang   +7 more
wiley   +1 more source

Interplay of Host and Viral Genetic Variations in Modulating Antibody Responses to Genotype 3a Hepatitis C Virus: Implications for Vaccine Design [PDF]

open access: gold
Wang Zhi-qing   +13 more
openalex   +1 more source

Viral Vaccines

open access: yes, 2017
openaire   +1 more source

[Viral mucosal vaccines].

open access: yesVoprosy virusologii, 1999
Reviews published reports on the development of mucosal antiviral vaccines administered through the mucous membranes and inducing systemic and local immunity. Describes methods ensuring the optimal conditions for penetration of mucosal vaccines in mucosal cells and discusses the possibility of local immunity induction in the vagina and rectum after ...
openaire   +1 more source

The complexity of dementia development and its comorbidities: The collaborative cross‐mouse population for multivarious tasks approach

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The increasing prevalence of dementia and related neurodegenerative diseases—including Alzheimer's disease, Parkinson's disease, multiple sclerosis, and amyotrophic lateral sclerosis—poses a growing public health challenge. These conditions have traditionally been studied as isolated central nervous system disorders, but emerging evidence points to ...
Osayd Zohud   +3 more
wiley   +1 more source

94 Changes in cytokine concentrations among beef cattle that had a normal and abnormal estrous cycle after vaccination with a modified live viral vaccine: A meta-analysis [PDF]

open access: bronze
Haley N Weidman   +12 more
openalex   +1 more source

Data from A Viral Vaccine Encoding Prostate-Specific Antigen Induces Antigen Spreading to a Common Set of Self-Proteins in Prostate Cancer Patients

open access: gold, 2023
Nancy J. Nesslinger   +6 more
openalex   +1 more source

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