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Caught in the act: the invasion of a viral vector changes viral prevalence and titre in native honeybees and bumblebees. [PDF]
Biol LettDobelmann J, Manley R, Wilfert L.
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Non-Viral Vector-Mediated Gene Therapy for ALS: Challenges and Future Perspectives.
Molecular Pharmaceutics, 2021Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease, for which no effective treatment is yet available to either slow or terminate it.
Gayathri R Ediriweera +4 more
semanticscholar +1 more source
VacciTUTOR, 2021
Viral vector vaccines use harmless, non-replicating or replicating viruses to deliver genetic material for production of vaccine antigens into host cell cytoplasm.
V. Oriol Mathieu +3 more
semanticscholar +1 more source
Viral vector vaccines use harmless, non-replicating or replicating viruses to deliver genetic material for production of vaccine antigens into host cell cytoplasm.
V. Oriol Mathieu +3 more
semanticscholar +1 more source
Current Opinion in Biotechnology, 1999
The field of viral vector targeting is advancing rapidly. Recent advances include the successful use of bifunctional crosslinkers to target adenoviral and retroviral vectors, elucidation of the crystal structures of an adenoviral and a retroviral receptor-binding domain, and definition of strategies for inserting short targeting peptides and larger ...
K W, Peng, S J, Russell
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The field of viral vector targeting is advancing rapidly. Recent advances include the successful use of bifunctional crosslinkers to target adenoviral and retroviral vectors, elucidation of the crystal structures of an adenoviral and a retroviral receptor-binding domain, and definition of strategies for inserting short targeting peptides and larger ...
K W, Peng, S J, Russell
openaire +2 more sources
Recommendations for the Development of Cell-Based Anti-Viral Vector Neutralizing Antibody Assays
AAPS Journal, 2020Viral vector–based gene therapies (GTx) have received significant attention in the recent years and the number of ongoing GTx clinical trials is increasing. A platform of choice for many of these studies is adeno-associated virus (AAV). All humans may be
B. Gorovits +6 more
semanticscholar +1 more source
2011
Viral vector is the most effective means of gene transfer to modify specific cell type or tissue and can be manipulated to express therapeutic genes. Several virus types are currently being investigated for use to deliver genes to cells to provide either transient or permanent transgene expression.
James N, Warnock +2 more
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Viral vector is the most effective means of gene transfer to modify specific cell type or tissue and can be manipulated to express therapeutic genes. Several virus types are currently being investigated for use to deliver genes to cells to provide either transient or permanent transgene expression.
James N, Warnock +2 more
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Viral Vectors for Gene Therapy
Pharmacology & Therapeutics, 1998Viruses have evolved to become highly efficient at nucleic acid delivery to specific cell types while avoiding immunosurveillance by an infected host. These properties make viruses attractive gene-delivery vehicles, or vectors, for gene therapy. Several types of viruses, including retrovirus, adenovirus, adeno-associated virus (AAV), and herpes simplex
P D, Robbins, S C, Ghivizzani
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Current Gene Therapy, 2002
Traditionally, vectors for gene transfer/therapy experiments were mono- or bicistronic. In the latter case, vectors express the gene of interest coupled with a marker gene. An increasing demand for more complex polycistronic vectors has arisen in recent years to obtain complex gene transfer/therapy effects.
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Traditionally, vectors for gene transfer/therapy experiments were mono- or bicistronic. In the latter case, vectors express the gene of interest coupled with a marker gene. An increasing demand for more complex polycistronic vectors has arisen in recent years to obtain complex gene transfer/therapy effects.
openaire +2 more sources