Results 161 to 170 of about 5,078 (274)

Tariff: The Most Beautiful Word in the Dictionary?

open access: yesReview of International Economics, EarlyView.
ABSTRACT We consider the welfare impacts of US tariff policy at levels proposed by President Donald J. Trump. General‐equilibrium simulations under a widely used transparent one‐sector trade model reveal sizable US welfare losses. When we extend the model to include bilateral firm selection and high resolution input–output linkages, the US losses ...
Edward J. Balistreri   +2 more
wiley   +1 more source

TMEM16A channel signalling microdomains in the regulation of vascular function

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic representation of TMEM16A channel signalling microdomains. Calcium influx or calcium release from the endoplasmic/sarcoplasmic reticulum (ER/SR) activates TMEM16A channels through interactions with regulatory proteins in vascular smooth muscle cells or endothelial cells. TMEM16A channel activation drives chloride efflux,
Fênix Araujo, Swapnil K. Sonkusare
wiley   +1 more source

Mitochondrial Ca2+ uniporter haploinsufficiency leads to sexually dimorphic redox imbalance and metabolic remodelling in the mouse brain

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The genetic inactivation of one Mcu allele leads to sex‐specific changes in neuronal function in adult mice, that is, the firing of action potentials and the relationship between cytosolic and mitochondrial Ca2+ levels. The ability to produce NAD(P)H by stimulated neural tissue is largely preserved in male mice but delayed in ...
Jenna Gray   +16 more
wiley   +1 more source

CRISPR-Drug Combinatorial Screening Identifies Effective Combination Treatments for MTAP-Deleted Cancer. [PDF]

open access: yesCancer Res
Knoll N   +21 more
europepmc   +1 more source

Extracellular ionic concentration modulates arrhythmias in a simulated population of human ventricular myocytes with long QT syndrome type 3

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic illustrating the in silico study pipeline. A total of 50,000 virtual myocytes were generated, which were then filtered to 7093 myocytes that fit experimentally constrained biomarkers for physiological electrical and calcium behaviour under wild‐type conditions.
Katherine Flannery   +3 more
wiley   +1 more source

Bodies and Bites: a medical school program that teaches anatomy, physiology, and nutrition to elementary school kids. [PDF]

open access: yesFront Public Health
Butterfield K   +7 more
europepmc   +1 more source

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