Results 181 to 190 of about 517,992 (346)

Is Virology Dead?

open access: yesmBio, 2014
Daniel DiMaio
doaj   +1 more source

ADAR1 mRNA quantification for predicting HSIL in persons with HIV and abnormal anal cytology

open access: yesInternational Journal of Cancer, EarlyView.
What's New? This study introduces ADAR1 mRNA quantification as a promising biomarker for improving high‐grade squamous intraepithelial lesion (HSIL) prediction in HIV‐positive individuals with abnormal anal cytology. With 92% specificity, it reduces unnecessary high‐resolution anoscopies (HRA) by 77%, offering a more efficient and targeted screening ...
Melissa Bello‐Perez   +15 more
wiley   +1 more source

Unveiling Origin Pitfalls in Metagenomic Surveillance for Emerging Infectious Diseases: Parvoviruses as a Model

open access: yesiMetaMed, EarlyView.
A diverse reagent‐associated virome, including parvoviruses, misleads zoonotic surveillance. By leveraging large language models (ChatGPT‐4o), we construct a virus discovery data framework (PVDDC) and ParvoDB to access and correct host misattributions, thereby enhancing the accuracy of metagenomic surveillance for emerging zoonotic diseases.
Peng Zhao   +11 more
wiley   +1 more source

Effects of SADS‐CoV accessory proteins NS3a, NS7a, and NS7b on viral pathogenicity: A multi‐omics investigation

open access: yesiMetaOmics, EarlyView.
This study has elucidated the role of three swine acute diarrhea syndrome coronavirus (SADS‐CoV) accessory proteins in influencing viral pathogenicity and preliminarily explored the host molecular targets and pathways affected by the NS3a, NS7a, and NS7b proteins of SADS‐CoV.
Xiaoling Yan   +7 more
wiley   +1 more source

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